{"action_type": {"action_type": "INHIBITOR", "description": "Negatively effects (inhibits) the normal functioning of the protein e.g., prevention of enzymatic reaction or activation of downstream pathway", "parent_type": "NEGATIVE MODULATOR"}, "activity_comment": null, "activity_id": 24507792, "activity_properties": [{"comments": null, "relation": "=", "result_flag": 0, "standard_relation": "=", "standard_text_value": null, "standard_type": "TIME", "standard_units": "hr", "standard_value": "32.0", "text_value": null, "type": "Time", "units": "hrs", "value": "32.0"}], "assay_chembl_id": "CHEMBL5054968", "assay_description": "Inhibition of Beta-hematin in Plasmodium falciparum cells assessed as hemozoin formation after 32 hrs by NP40 detergent-mediated assay", "assay_type": "B", "assay_variant_accession": null, "assay_variant_mutation": null, "bao_endpoint": "BAO_0000190", "bao_format": "BAO_0000019", "bao_label": "assay format", "canonical_smiles": "CCCCCc1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21", "data_validity_comment": null, "data_validity_description": null, "document_chembl_id": "CHEMBL5053539", "document_journal": "Bioorg Med Chem Lett", "document_year": 2021, "ligand_efficiency": null, "modality": null, "molecule_chembl_id": "CHEMBL465", "molecule_pref_name": "DRONABINOL", "parent_molecule_chembl_id": "CHEMBL465", "pchembl_value": "4.95", "potential_duplicate": 0, "qudt_units": "http://www.openphacts.org/units/Nanomolar", "record_id": 3837377, "relation": "=", "src_id": 1, "standard_flag": 1, "standard_relation": "=", "standard_text_value": null, "standard_type": "IC50", "standard_units": "nM", "standard_upper_value": null, "standard_value": "11300.0", "target_chembl_id": "CHEMBL613898", "target_organism": "Plasmodium falciparum", "target_pref_name": "Hemozoin", "target_tax_id": "5833", "text_value": null, "toid": null, "type": "IC50", "units": "uM", "uo_units": "UO_0000065", "upper_value": null, "value": "11.3"}