CHEBI:76749 - bopindolol

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name bopindolol
ChEBI ID CHEBI:76749
Definition A racemate comprising of equal amounts of (R)-bopindolol and (S)-bopindolol. It is a non-selective antagonist of β1- and β2-adrenoceptors and a prodrug in which the ester group is hydrolysed to form the corresponding hydroxy derivative.
Stars This entity has been manually annotated by the ChEBI Team.
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Roles Classification
Biological Role(s): beta-adrenergic antagonist
An agent that binds to but does not activate beta-adrenergic receptors thereby blocking the actions of endogenous or exogenous beta-adrenergic agonists. beta-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
Application(s): antihypertensive agent
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
beta-adrenergic antagonist
An agent that binds to but does not activate beta-adrenergic receptors thereby blocking the actions of endogenous or exogenous beta-adrenergic agonists. beta-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing bopindolol (CHEBI:76749) has part (R)-bopindolol (CHEBI:143780)
bopindolol (CHEBI:76749) has part (S)-bopindolol (CHEBI:143781)
bopindolol (CHEBI:76749) has role β-adrenergic antagonist (CHEBI:35530)
bopindolol (CHEBI:76749) has role antihypertensive agent (CHEBI:35674)
bopindolol (CHEBI:76749) is a racemate (CHEBI:60911)
IUPAC Name
rac-1-(tert-butylamino)-3-[(2-methyl-1H-indol-4-yl)oxy]propan-2-yl benzoate
INNs Sources
bopindolol WHO MedNet
bopindolol WHO MedNet
bopindolol WHO MedNet
bopindololum WHO MedNet
Synonyms Sources
(±)-1-[(1,1-Dimethylethyl)amino]-3-[(2-methyl-1H-indol-4-yl)oxy]-2-propanol benzoate ChEBI
(±)-bopindolol ChemIDplus
(RS)-bopindolol ChEBI
LT 31-200 ChemIDplus
rac-bopindolol ChEBI
racemic bopindolol ChEBI
Brand Name Source
Sandonorm KEGG DRUG
Manual Xrefs Databases
389 DrugCentral
40146 ChemSpider
Bopindolol Wikipedia
D07537 KEGG DRUG
DB08807 DrugBank
HMDB0015696 HMDB
LSM-45796 LINCS
View more database links
Registry Numbers Types Sources
62658-63-3 CAS Registry Number ChemIDplus
62658-63-3 CAS Registry Number DrugBank
Citations Waiting for Citations Types Sources
10474078 PubMed citation Europe PMC
11314603 PubMed citation Europe PMC
11906483 PubMed citation Europe PMC
12008130 PubMed citation Europe PMC
14656606 PubMed citation Europe PMC
1681490 PubMed citation Europe PMC
22477063 PubMed citation Europe PMC
2439815 PubMed citation Europe PMC
2568836 PubMed citation Europe PMC
32888198 PubMed citation Europe PMC
6127218 PubMed citation Europe PMC
7474556 PubMed citation Europe PMC
7902696 PubMed citation Europe PMC
8097742 PubMed citation Europe PMC
8535397 PubMed citation Europe PMC
9730775 PubMed citation Europe PMC
Last Modified
14 July 2021