CHEBI:5693 - hexachlorophene

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ChEBI Name hexachlorophene
ChEBI ID CHEBI:5693
Definition An organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disorders. It is also used in agriculture as an acaricide and fungicide, but is not approved for such use within the European Union.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C13H6Cl6O2
Net Charge 0
Average Mass 406.90400
Monoisotopic Mass 403.850
InChI InChI=1S/C13H6Cl6O2/c14-6-2-8(16)12(20)4(10(6)18)1-5-11(19)7(15)3-9(17)13(5)21/h2-3,20-21H,1H2
InChIKey ACGUYXCXAPNIKK-UHFFFAOYSA-N
SMILES Oc1c(Cl)cc(Cl)c(Cl)c1Cc1c(O)c(Cl)cc(Cl)c1Cl
Roles Classification
Biological Role(s): antibacterial agent
A substance that kills or slows the growth of bacteria.
antifungal agrochemical
Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties.
fungicide
A substance used to destroy fungal pests.
(via bridged diphenyl fungicide )
antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
(via bridged diphenyl antifungal agent )
Application(s): antiseptic drug
A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body).
acaricide
A substance used to destroy pests of the subclass Acari (mites and ticks).
antifungal agrochemical
Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties.
fungicide
A substance used to destroy fungal pests.
(via bridged diphenyl fungicide )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing hexachlorophene (CHEBI:5693) has role acaricide (CHEBI:22153)
hexachlorophene (CHEBI:5693) has role antibacterial agent (CHEBI:33282)
hexachlorophene (CHEBI:5693) has role antifungal agrochemical (CHEBI:86328)
hexachlorophene (CHEBI:5693) has role antiseptic drug (CHEBI:48218)
hexachlorophene (CHEBI:5693) is a bridged diphenyl fungicide (CHEBI:87039)
hexachlorophene (CHEBI:5693) is a polyphenol (CHEBI:26195)
hexachlorophene (CHEBI:5693) is a trichlorobenzene (CHEBI:27096)
IUPAC Name
2,2'-methylenebis(3,4,6-trichlorophenol)
INNs Sources
hexachlorophene WHO MedNet
hexachlorophène WHO MedNet
hexachlorophenum WHO MedNet
hexaclorofeno WHO MedNet
Synonyms Sources
2,2',3,3',5,5'-hexachloro-6,6'-dihydroxydiphenylmethane NIST Chemistry WebBook
2,2'-dihydroxy-3,3',5,5',6,6'-hexachlorodiphenylmethane NIST Chemistry WebBook
2,2'-dihydroxy-3,5,6,3',5',6'-hexachlorodiphenylmethane NIST Chemistry WebBook
2,2'-methanediylbis(3,4,6-trichlorophenol) PDBeChem
bis(2-hydroxy-3,5,6-trichlorophenyl)methane NIST Chemistry WebBook
bis(3,5,6-trichloro-2-hydroxyphenyl)methane NIST Chemistry WebBook
Brand Names Sources
Acigena ChemIDplus
Almederm ChemIDplus
Armohex ChemIDplus
Distodin ChemIDplus
Esaclorofene ChemIDplus
Exofene ChemIDplus
Gamophen ChemIDplus
Gamophene ChemIDplus
Germa-medica ChemIDplus
Hexa-Germ ChemIDplus
Hexabalm ChemIDplus
Hexafen ChemIDplus
Hexascrub ChemIDplus
Hexide ChemIDplus
Nabac ChemIDplus
Phiso-Scrub ChemIDplus
Phisodan ChemIDplus
Septi-Soft ChemIDplus
Septisol ChemIDplus
Septofen ChemIDplus
Solu-Heks ChemIDplus
Soy-Dome ChemIDplus
Staphene O ChemIDplus
Ster-Zac ChemIDplus
Steral ChemIDplus
Steraskin ChemIDplus
Surgi-Cen ChemIDplus
Surgi-cin ChemIDplus
Surofene ChemIDplus
Tersaseptic ChemIDplus
Turgex ChemIDplus
Database Links Databases
1364 DrugCentral
C08039 KEGG COMPOUND
D00859 KEGG DRUG
DB00756 DrugBank
H3P PDBeChem
Hexachlorophene Wikipedia
HMDB0014894 HMDB
LSM-6032 LINCS
US2250480 Patent
US2435593 Patent
US2812365 Patent
View more database links
Registry Numbers Types Sources
2064407 Reaxys Registry Number Reaxys
70-30-4 CAS Registry Number NIST Chemistry WebBook
70-30-4 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
1133685 PubMed citation Europe PMC
22313968 PubMed citation Europe PMC
23251633 PubMed citation Europe PMC
397166 PubMed citation Europe PMC
894425 PubMed citation Europe PMC
952574 PubMed citation Europe PMC
Last Modified
22 February 2017