CHEBI:9728 - trimethaphan

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ChEBI Name trimethaphan
Definition A complex heterocyclic sulfonium compound with an imidazolium core, used to treat hypertension.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C22H25N2OS
Net Charge +1
Average Mass 365.51200
Monoisotopic Mass 365.16821
InChI InChI=1S/C22H25N2OS/c25-22-23(14-17-8-3-1-4-9-17)19-16-26-13-7-12-20(26)21(19)24(22)15-18-10-5-2-6-11-18/h1-6,8-11,19-21H,7,12-16H2/q+1
SMILES O=C1N(Cc2ccccc2)C2C[S+]3CCCC3C2N1Cc1ccccc1
Roles Classification
Biological Role(s): nicotinic antagonist
An antagonist at the nicotinic cholinergic receptor.
Application(s): anaesthesia adjuvant
Any substance that possesses little anaesthetic effect by itself, but which enhances or potentiates the anaesthetic action of other drugs when given at the same time.
vasodilator agent
A drug used to cause dilation of the blood vessels.
antihypertensive agent
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
nicotinic antagonist
An antagonist at the nicotinic cholinergic receptor.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing trimethaphan (CHEBI:9728) has role anaesthesia adjuvant (CHEBI:60807)
trimethaphan (CHEBI:9728) has role antihypertensive agent (CHEBI:35674)
trimethaphan (CHEBI:9728) has role nicotinic antagonist (CHEBI:48878)
trimethaphan (CHEBI:9728) has role vasodilator agent (CHEBI:35620)
trimethaphan (CHEBI:9728) is a sulfonium compound (CHEBI:26830)
Incoming trimethaphan camsylate (CHEBI:9729) has part trimethaphan (CHEBI:9728)
Synonyms Sources
Trimetaphan ChemIDplus
Trimetaphanum ChemIDplus
Trimethaphan KEGG COMPOUND
Manual Xrefs Databases
2752 DrugCentral
DB01116 DrugBank
View more database links
Registry Number Type Source
7187-66-8 CAS Registry Number ChemIDplus
Last Modified
22 February 2017