CHEBI:9674 - triazolam

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ChEBI Name triazolam
ChEBI ID CHEBI:9674
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C17H12Cl2N4
Net Charge 0
Average Mass 343.20954
Monoisotopic Mass 342.044
InChI InChI=1S/C17H12Cl2N4/c1-10-21-22-16-9-20-17(12-4-2-3-5-14(12)19)13-8-11(18)6-7-15(13)23(10)16/h2-8H,9H2,1H3
InChIKey JOFWLTCLBGQGBO-UHFFFAOYSA-N
SMILES Cc1nnc2CN=C(c3ccccc3Cl)c3cc(Cl)ccc3-n12
Roles Classification
Biological Role(s): GABA modulator
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
(via benzodiazepine )
Application(s): sedative
A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
GABA modulator
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
(via benzodiazepine )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing triazolam (CHEBI:9674) has role sedative (CHEBI:35717)
triazolam (CHEBI:9674) is a triazolobenzodiazepine (CHEBI:35501)
IUPAC Name
8-chloro-6-(2-chlorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
Synonym Source
Halcion ChemIDplus
Manual Xrefs Databases
2729 DrugCentral
D00387 KEGG DRUG
DB00897 DrugBank
Triazolam Wikipedia
View more database links
Registry Numbers Types Sources
1226643 Beilstein Registry Number Beilstein
28911-01-5 CAS Registry Number ChemIDplus
Last Modified
22 February 2017