CHEBI:9637 - torasemide

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name torasemide
ChEBI ID CHEBI:9637
Definition An N-sulfonylurea obtained by formal condensation of [(3-methylphenyl)amino]pyridine-3-sulfonic acid with the free amino group of N-isopropylurea.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C16H20N4O3S
Net Charge 0
Average Mass 348.42000
Monoisotopic Mass 348.126
InChI InChI=1S/C16H20N4O3S/c1-11(2)18-16(21)20-24(22,23)15-10-17-8-7-14(15)19-13-6-4-5-12(3)9-13/h4-11H,1-3H3,(H,17,19)(H2,18,20,21)
InChIKey NGBFQHCMQULJNZ-UHFFFAOYSA-N
SMILES CC(C)NC(=O)NS(=O)(=O)c1cnccc1Nc1cccc(C)c1
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Application(s): antihypertensive agent
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
loop diuretic
A diuretic that acts on the ascending loop of Henle in the kidney.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing torasemide (CHEBI:9637) has functional parent 4-aminopyridine (CHEBI:34385)
torasemide (CHEBI:9637) has role antihypertensive agent (CHEBI:35674)
torasemide (CHEBI:9637) has role loop diuretic (CHEBI:77608)
torasemide (CHEBI:9637) is a N-sulfonylurea (CHEBI:76983)
torasemide (CHEBI:9637) is a aminopyridine (CHEBI:38207)
torasemide (CHEBI:9637) is a secondary amino compound (CHEBI:50995)
IUPAC Names
N-(isopropylcarbamoyl)-4-[(3-methylphenyl)amino]pyridine-3-sulfonamide
N-[(propan-2-yl)carbamoyl]-4-[(3-methylphenyl)amino]pyridine-3-sulfonamide
INNs Sources
torasemida DrugBank
torasémide WHO MedNet
torasemide KEGG DRUG
torasemidum DrugBank
Synonyms Sources
1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea ChemIDplus
N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide ChemIDplus
Torsemide KEGG DRUG
Brand Names Sources
Demadex KEGG DRUG
Luprac KEGG DRUG
Manual Xrefs Databases
2708 DrugCentral
D00382 KEGG DRUG
DB00214 DrugBank
HMDB0014359 HMDB
LSM-2662 LINCS
Torasemide Wikipedia
View more database links
Registry Numbers Types Sources
498515 Reaxys Registry Number Reaxys
56211-40-6 CAS Registry Number ChemIDplus
56211-40-6 CAS Registry Number KEGG DRUG
Citations Waiting for Citations Types Sources
21391491 PubMed citation Europe PMC
21906812 PubMed citation Europe PMC
22030290 PubMed citation Europe PMC
22364690 PubMed citation Europe PMC
22407343 PubMed citation Europe PMC
23013124 PubMed citation Europe PMC
23237447 PubMed citation Europe PMC
23792294 PubMed citation Europe PMC
23837587 PubMed citation Europe PMC
23877845 PubMed citation Europe PMC
24040049 PubMed citation Europe PMC
24243991 PubMed citation Europe PMC
24367917 PubMed citation Europe PMC
24432564 PubMed citation Europe PMC
24554915 PubMed citation Europe PMC
Last Modified
22 February 2017