CHEBI:9620 - tolnaftate

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ChEBI Name tolnaftate
Definition A monothiocarbamic ester that is the methyl(3-tolyl)carbamothioate ester of 2-naphthol. A synthetic anti-fungal agent used to treat jock itch, athlete's foot and ringworm.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C19H17NOS
Net Charge 0
Average Mass 307.40900
Monoisotopic Mass 307.10309
InChI InChI=1S/C19H17NOS/c1-14-6-5-9-17(12-14)20(2)19(22)21-18-11-10-15-7-3-4-8-16(15)13-18/h3-13H,1-2H3
SMILES CN(C(=S)Oc1ccc2ccccc2c1)c1cccc(C)c1
Roles Classification
Biological Role(s): antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
Application(s): antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
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ChEBI Ontology
Outgoing tolnaftate (CHEBI:9620) has functional parent 2-naphthol (CHEBI:10432)
tolnaftate (CHEBI:9620) has role antifungal drug (CHEBI:86327)
tolnaftate (CHEBI:9620) is a monothiocarbamic ester (CHEBI:38128)
O-2-naphthyl methyl(3-methylphenyl)carbamothioate
INNs Sources
tolnaftate WHO MedNet
tolnaftate KEGG DRUG
tolnaftato DrugBank
tolnaftatum DrugBank
Synonyms Sources
2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate ChemIDplus
m,N-Dimethylthiocarbanilic acid O-2-naphthyl ester ChemIDplus
Methyl (3-methylphenyl)carbamothioic acid O-2-naphthalenyl ester NIST Chemistry WebBook
N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide HMDB
O-2-Naphthyl m,N-dimethylthiocarbanilate ChemIDplus
Tolnaphthate NIST Chemistry WebBook
Brand Names Sources
Tinactin KEGG DRUG
Manual Xrefs Databases
3617 DrugCentral
DB00525 DrugBank
HMDB0005005 HMDB
Tolnaftate Wikipedia
US2010035939 Patent
WO2010037089 Patent
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Registry Numbers Types Sources
2398-96-1 CAS Registry Number NIST Chemistry WebBook
2398-96-1 CAS Registry Number ChemIDplus
2398-96-1 CAS Registry Number KEGG DRUG
2752620 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
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Last Modified
22 February 2017