CHEBI:2686 - amrinone

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name amrinone
ChEBI ID CHEBI:2686
Definition A 3,4'-bipyridine subsituted at positions 5 and 6 by an amino group and a keto function respectively. A pyridine phosphodiesterase 3 inhibitor, it is a drug that may improve the prognosis in patients with congestive heart failure.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:95269
Supplier Information
Download Molfile XML SDF
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C10H9N3O
Net Charge 0
Average Mass 187.198
Monoisotopic Mass 187.075
InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14)
InChIKey RNLQIBCLLYYYFJ-UHFFFAOYSA-N
SMILES C1=CN=CC=C1C2=CNC(=O)C(=C2)N
Roles Classification
Biological Role(s): EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a phosphoric diester hydrolase (EC 3.1.4.*).
View more via ChEBI Ontology
ChEBI Ontology
Outgoing amrinone (CHEBI:2686) has role EC 3.1.4.* (phosphoric diester hydrolase) inhibitor (CHEBI:50218)
amrinone (CHEBI:2686) is a bipyridines (CHEBI:50511)
IUPAC Name
5-amino[3,4'-bipyridin]-6(1H)-one
INN Source
amrinone ChemIDplus
Manual Xrefs Databases
Amrinone Wikipedia
D00231 KEGG DRUG
LSM-6600 LINCS
View more database links
Registry Numbers Types Sources
60719-84-8 CAS Registry Number DrugCentral
60719-84-8 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
15064331 PubMed citation Europe PMC
15892406 PubMed citation Europe PMC
16154150 PubMed citation Europe PMC
18468627 PubMed citation Europe PMC
23908328 PubMed citation Europe PMC
28166217 PubMed citation Europe PMC
Last Modified
13 June 2017