InChI=1S/C34H50O12/c1- 9- 12- 13- 14- 15- 17- 24(37) 43- 28- 26- 25(20(5) 27(28) 44- 30(38) 19(4) 11- 3) 29- 34(41,33(8,40) 31(39) 45- 29) 22(42- 23(36) 16- 10- 2) 18- 32(26,7) 46- 21(6) 35/h11,22,26- 29,40- 41H,9- 10,12- 18H2,1- 8H3/b19- 11- /t22- ,26+,27- ,28- ,29- ,32- ,33+,34+/m0/s1 |
IXFPJGBNCFXKPI-FSIHEZPISA-N |
[H] [C@@] 1(OC(=O) C(\C) =C/C) [C@@H] (OC(=O) CCCCCCC) [C@@] 2([H] ) C(=C1C) [C@] 1([H] ) OC(=O) [C@@] (C) (O) [C@@] 1(O) [C@H] (C[C@] 2(C) OC(C) =O) OC(=O) CCC |
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EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor
An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of Ca2+-transporting ATPase (EC 3.6.3.8).
calcium channel blocker
One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools.
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View more via ChEBI Ontology
(3S,3aR,4S,6S,6aR,7S,8S,9bS)- 6- (acetyloxy)- 4- (butanoyloxy)- 3,3a- dihydroxy- 3,6,9- trimethyl- 8- {[(2Z)- 2- methylbut- 2- enoyl]oxy}- 2- oxo- 2,3,3a,4,5,6,6a,7,8,9b- decahydroazuleno[4,5- b]furan- 7- yl octanoate
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octanoic acid {3S- [3α,3aβ,4α,6β,6aβ,7β,8α(Z),9bα]}- 6- (acetoxy)- 2,3,3a,4,5,6,6a,7,8,9b- decahydro- 3,3a- dihydroxy- 3,6,9- trimethyl- 8- [(2- methyl- 1- oxo- 2- butenyl)oxy]- 2- oxo- 4- (1- oxobutoxy)- azuleno[4,5- b]furan- 7- yl ester
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ChEBI
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Tg
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ChEBI
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Thapsigargin
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KEGG COMPOUND
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thapsigargine
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ChEBI
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4649293
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Beilstein Registry Number
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Beilstein
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4649293
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Reaxys Registry Number
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Reaxys
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67526-95-8
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CAS Registry Number
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ChemIDplus
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10477042
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PubMed citation
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Europe PMC
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12410314
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PubMed citation
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Europe PMC
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16874404
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PubMed citation
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Europe PMC
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17825049
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PubMed citation
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Europe PMC
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20357004
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PubMed citation
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Europe PMC
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24598360
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PubMed citation
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Europe PMC
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9014219
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PubMed citation
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Europe PMC
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