CHEBI:9451 - terconazole

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ChEBI Name terconazole
ChEBI ID CHEBI:9451
Definition A racemate consisting of equimolar amounts of (2R,4S)- and (2S,4R)-terconazole. It has broad-spectrum antifungal activitiy and is used for the treatment of vaginal yeast infections (Candida).
Stars This entity has been manually annotated by the ChEBI Team.
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Roles Classification
Biological Role(s): antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
(via conazole antifungal drug )
(via triazole antifungal drug )
ergosterol biosynthesis inhibitor
Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol.
(via conazole antifungal agent )
antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
(via conazole antifungal agent )
(via triazole antifungal agent )
Application(s): antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
(via conazole antifungal drug )
(via triazole antifungal drug )
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ChEBI Ontology
Outgoing terconazole (CHEBI:9451) has part (2R,4S)-terconazole (CHEBI:82980)
terconazole (CHEBI:9451) has part (2S,4R)-terconazole (CHEBI:82981)
terconazole (CHEBI:9451) is a conazole antifungal drug (CHEBI:87071)
terconazole (CHEBI:9451) is a racemate (CHEBI:60911)
terconazole (CHEBI:9451) is a triazole antifungal drug (CHEBI:87101)
IUPAC Name
rac-1-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine
INNs Sources
terconazol WHO MedNet
terconazole WHO MedNet
terconazole WHO MedNet
terconazolum WHO MedNet
Synonyms Sources
cis-1-(p-{[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine ChemIDplus
R 42,470 ChemIDplus
R-42,470 ChemIDplus
R-42470 ChEBI
Brand Names Sources
Terazol 3 KEGG DRUG
Terazol 7 ChEBI
Manual Xrefs Databases
C08080 KEGG COMPOUND
D00888 KEGG DRUG
DB00251 DrugBank
HMDB0014396 HMDB
Terconazole Wikipedia
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Registry Numbers Types Sources
67915-31-5 CAS Registry Number KEGG COMPOUND
67915-31-5 CAS Registry Number ChemIDplus
7471103 Reaxys Registry Number Reaxys
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Last Modified
22 February 2017