CHEBI:6539 - Lorazepam

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name Lorazepam
ChEBI ID CHEBI:6539
Stars This entity has been manually annotated by a third party.
Secondary ChEBI IDs CHEBI:94326
Supplier Information
Download Molfile XML SDF
Formulae C15H10Cl2N2O2
C15H10Cl2N2O2
Net Charge 0
Average Mass 321.159
Monoisotopic Mass 320.012
InChI InChI=1S/C15H10Cl2N2O2/c16-8-5-6-12-10(7-8)13(19-15(21)14(20)18-12)9-3-1-2-4-11(9)17/h1-7,15,21H,(H,18,20)
InChIKey DIWRORZWFLOCLC-UHFFFAOYSA-N
SMILES C1=CC=C(C(=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)O)Cl
Roles Classification
Biological Role(s): GABA modulator
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
(via benzodiazepine )
Application(s): GABA modulator
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
(via benzodiazepine )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing Lorazepam (CHEBI:6539) is a benzodiazepine (CHEBI:22720)
Synonyms Sources
ativan DrugCentral
Lorazepam KEGG COMPOUND
Wy 4036 DrugCentral
Wy-4036 DrugCentral
Manual Xrefs Databases
1606 DrugCentral
D00365 KEGG DRUG
LSM-4970 LINCS
View more database links
Registry Number Type Source
846-49-1 CAS Registry Number DrugCentral
Last Modified
06 March 2017