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streptozocin (CHEBI:9288)

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ChEBI Name streptozocin
ChEBI ID CHEBI:9288
Definition An antibiotic that is produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula Source
C8H15N3O7 KEGG COMPOUND
Net Charge 0
Average Mass 265.22072
InChI
InChI=1S/C8H15N3O7/c1-11(10-17)8(16)9-4-6(14)5(13)3(2-12)18-7(4)15/h3-7,12-15H,2H2,1H3,(H,9,16)/t3-,4-,5-,6-,7+/m1/s1
InChIKey
ZSJLQEPLLKMAKR-GKHCUFPYSA-N
SMILES
CN(N=O)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O
Roles Classification
Chemical Role(s): DNA synthesis inhibitor
Any substance that inhibits the synthesis of DNA.
Biological Role(s): DNA synthesis inhibitor
Any substance that inhibits the synthesis of DNA.
secondary metabolite
A metabolite that is not directly involved in the normal growth, development or reproduction of an organism.
antibiotic
A substance that is biostatic or biocidal at low concentrations towards bacteria, yeasts, moulds, or other form of life, especially pathogenic or noxious organisms. Although the term was originally restricted to substances produced by microorganisms, its use was later expanded to include derivatives of such substances and it is now commonly used to include entirely synthetic compounds.
Application(s): antibiotic
A substance that is biostatic or biocidal at low concentrations towards bacteria, yeasts, moulds, or other form of life, especially pathogenic or noxious organisms. Although the term was originally restricted to substances produced by microorganisms, its use was later expanded to include derivatives of such substances and it is now commonly used to include entirely synthetic compounds.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more on the ChEBI Ontology
ChEBI Ontology
Outgoing streptozocin (CHEBI:9288) has role antibiotic (CHEBI:22582)
streptozocin (CHEBI:9288) has role antineoplastic agent (CHEBI:35610)
streptozocin (CHEBI:9288) has role DNA synthesis inhibitor (CHEBI:59517)
streptozocin (CHEBI:9288) has role secondary metabolite (CHEBI:26619)
streptozocin (CHEBI:9288) is a N-acylglucosamine (CHEBI:21638)
streptozocin (CHEBI:9288) is a N-nitrosoureas (CHEBI:76551)
IUPAC Name
2-deoxy-2-{[methyl(nitroso)carbamoyl]amino}-α-D-glucopyranose
INNs Sources
estreptozocina ChemIDplus
streptozocin KEGG DRUG
streptozocine DrugBank
streptozocinum DrugBank
Synonyms Sources
2-Deoxy-2-(((methylnitrosoamino)carbonyl)amino)-D-glucopyranose ChemIDplus
2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose ChEBI
N-D-Glucosyl-(2)-N'-nitrosomethylharnstoff ChemIDplus
N-D-Glucosyl-(2)-N'-nitrosomethylurea ChemIDplus
Streptozocinium DrugBank
Streptozotocin ChemIDplus
Database Links Databases
C07313 KEGG COMPOUND
D05932 KEGG DRUG
DB00428 DrugBank
FR1434920 Patent
HMDB14572 HMDB
Streptozocin Wikipedia
US2005271747 Patent
US2005272738 Patent
US2008085882 Patent
US4156777 Patent
View more database links
Registry Numbers Types Sources
18883-66-4 CAS Registry Number KEGG COMPOUND
18883-66-4 CAS Registry Number ChemIDplus
2060675 Beilstein Registry Number Beilstein
2060675 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
12613763 PubMed citation CiteXplore
23151907 PubMed citation CiteXplore
23333576 PubMed citation CiteXplore
23600389 PubMed citation CiteXplore
23612842 PubMed citation CiteXplore
23662406 PubMed citation CiteXplore
2954873 PubMed citation CiteXplore
Last Modified
12 February 2014

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