CHEBI:91107 - SB 415286

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ChEBI Name SB 415286
ChEBI ID CHEBI:91107
Definition A member of the class of maleimides carrying 3-chloro-4-hydroxyphenylamino and 2-nitrophenyl substituents at positions 3 and 4 respectively.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C16H10ClN3O5
Net Charge 0
Average Mass 359.721
Monoisotopic Mass 359.031
InChI InChI=1S/C16H10ClN3O5/c17-10-7-8(5-6-12(10)21)18-14-13(15(22)19-16(14)23)9-3-1-2-4-11(9)20(24)25/h1-7,21H,(H2,18,19,22,23)
InChIKey PQCXVIPXISBFPN-UHFFFAOYSA-N
SMILES N1C(C(=C(C1=O)NC2=CC=C(C(=C2)Cl)O)C3=CC=CC=C3[N+]([O-])=O)=O
Roles Classification
Chemical Role(s): antioxidant
A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): EC 2.7.11.26 (tau-protein kinase) inhibitor
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of tau-protein kinase inhibitor (EC 2.7.11.26).
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
Application(s): neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing SB 415286 (CHEBI:91107) has role antioxidant (CHEBI:22586)
SB 415286 (CHEBI:91107) has role apoptosis inducer (CHEBI:68495)
SB 415286 (CHEBI:91107) has role EC 2.7.11.26 (tau-protein kinase) inhibitor (CHEBI:91092)
SB 415286 (CHEBI:91107) has role neuroprotective agent (CHEBI:63726)
SB 415286 (CHEBI:91107) is a maleimides (CHEBI:55417)
SB 415286 (CHEBI:91107) is a monochlorobenzenes (CHEBI:83403)
SB 415286 (CHEBI:91107) is a nitrobenzenes (CHEBI:48109)
SB 415286 (CHEBI:91107) is a phenols (CHEBI:33853)
SB 415286 (CHEBI:91107) is a secondary amino compound (CHEBI:50995)
SB 415286 (CHEBI:91107) is a substituted aniline (CHEBI:48975)
IUPAC Name
3-(3-chloro-4-hydroxyanilino)-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione
Synonyms Sources
3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione ChemIDplus
SB-415286 ChemIDplus
SB415286 ChEBI
Manual Xref Database
LSM-3719 LINCS
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Registry Numbers Types Sources
264218-23-7 CAS Registry Number ChemIDplus
8795652 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
11279265 PubMed citation Europe PMC
11696357 PubMed citation Europe PMC
12950267 PubMed citation Europe PMC
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22776263 PubMed citation Europe PMC
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Last Modified
08 July 2016