lesinurad (CHEBI:90929)

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ChEBI Name	lesinurad

ChEBI ID	CHEBI:90929

Definition	A member of the class of triazoles that is [(3-bromo-1,2,4-triazol-5-yl)sulfanyl]acetic acid substituted at position 1 of the triazole ring by a 4-cyclopropylnaphthalen-1-yl group. Used for treatment of gout.

Stars	This entity has been manually annotated by the ChEBI Team.

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Formula

C17H14BrN3O2S

Net Charge

Average Mass

404.282

Monoisotopic Mass

402.99901

InChI

InChI=1S/C17H14BrN3O2S/c18-16-19-20-17(24-9-15(22)23)21(16)14-8-7-11(10-5-6-10)12-3-1-2-4-13(12)14/h1-4,7-8,10H,5-6,9H2,(H,22,23)

InChIKey

FGQFOYHRJSUHMR-UHFFFAOYSA-N

SMILES

C=1C=C(C2=C(C1N3C(=NN=C3Br)SCC(O)=O)C=CC=C2)C4CC4

Roles Classification
Chemical Role(s):	Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Bronsted base). (via oxoacid )

Application(s):	uricosuric drug A gout suppressant that acts directly on the renal tubule to increase the excretion of uric acid, thus reducing its concentrations in plasma.

ChEBI Ontology
Outgoing	lesinurad (CHEBI:90929) has role uricosuric drug (CHEBI:35841) lesinurad (CHEBI:90929) is a aryl sulfide (CHEBI:35683) lesinurad (CHEBI:90929) is a cyclopropanes (CHEBI:51454) lesinurad (CHEBI:90929) is a monocarboxylic acid (CHEBI:25384) lesinurad (CHEBI:90929) is a naphthalenes (CHEBI:25477) lesinurad (CHEBI:90929) is a organobromine compound (CHEBI:37141) lesinurad (CHEBI:90929) is a triazoles (CHEBI:35727)

IUPAC Name

{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid

INN	Source
lesinurad	ChemIDplus

Brand Name	Source
Zurampic	ChemIDplus

Last Modified

22 February 2017