CHEBI:90929 - lesinurad

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ChEBI Name lesinurad
Definition A member of the class of triazoles that is [(3-bromo-1,2,4-triazol-5-yl)sulfanyl]acetic acid substituted at position 1 of the triazole ring by a 4-cyclopropylnaphthalen-1-yl group. Used for treatment of gout.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C17H14BrN3O2S
Net Charge 0
Average Mass 404.282
Monoisotopic Mass 402.99901
InChI InChI=1S/C17H14BrN3O2S/c18-16-19-20-17(24-9-15(22)23)21(16)14-8-7-11(10-5-6-10)12-3-1-2-4-13(12)14/h1-4,7-8,10H,5-6,9H2,(H,22,23)
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Application(s): uricosuric drug
A gout suppressant that acts directly on the renal tubule to increase the excretion of uric acid, thus reducing its concentrations in plasma.
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ChEBI Ontology
Outgoing lesinurad (CHEBI:90929) has role uricosuric drug (CHEBI:35841)
lesinurad (CHEBI:90929) is a aryl sulfide (CHEBI:35683)
lesinurad (CHEBI:90929) is a cyclopropanes (CHEBI:51454)
lesinurad (CHEBI:90929) is a monocarboxylic acid (CHEBI:25384)
lesinurad (CHEBI:90929) is a naphthalenes (CHEBI:25477)
lesinurad (CHEBI:90929) is a organobromine compound (CHEBI:37141)
lesinurad (CHEBI:90929) is a triazoles (CHEBI:35727)
{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid
INN Source
lesinurad ChemIDplus
Synonyms Sources
RDEA 594 ChemIDplus
RDEA594 ChemIDplus
Brand Name Source
Zurampic ChemIDplus
Manual Xrefs Databases
5075 DrugCentral
Lesinurad Wikipedia
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Registry Numbers Types Sources
12932464 Reaxys Registry Number Reaxys
878672-00-5 CAS Registry Number ChemIDplus
878672-00-5 CAS Registry Number KEGG DRUG
Citations Waiting for Citations Types Sources
24509406 PubMed citation Europe PMC
24703353 PubMed citation Europe PMC
25603039 PubMed citation Europe PMC
26073200 PubMed citation Europe PMC
26165106 PubMed citation Europe PMC
26170627 PubMed citation Europe PMC
26742777 PubMed citation Europe PMC
Last Modified
22 February 2017