CHEBI:89627 - 5a-Tetrahydrocortisol

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ChEBI Name 5a-Tetrahydrocortisol
ChEBI ID CHEBI:89627
Stars This entity has been manually annotated by a third party.
Supplier Information
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Formula C21H34O5
Net Charge 0
Average Mass 366.492
Monoisotopic Mass 366.241
InChI InChI=1S/C21H34O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h12-16,18,22-24,26H,3-11H2,1-2H3/t12-,13+,14-,15-,16-,18+,19-,20-,21-/m0/s1
InChIKey AODPIQQILQLWGS-FDSHTENPSA-N
SMILES C1[C@H](C[C@]2([C@](C1)([C@@]3([C@@](CC2)([C@]4([C@](C[C@@H]3O)([C@](CC4)(C(=O)CO)O)C)[H])[H])[H])C)[H])O
Metabolite of Species Details
Homo sapiens (NCBI:txid9606) Found in blood (UBERON:0000178). See: PubMed
Homo sapiens (NCBI:txid9606) Found in urine (BTO:0001419). See: PubMed
Roles Classification
Biological Role(s): hormone
Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
(via steroid hormone )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing 5a-Tetrahydrocortisol (CHEBI:89627) is a corticosteroid hormone (CHEBI:36699)
IUPAC Name
2-hydroxy-1-[(1S,2S,5R,7S,10S,11S,14R,15S,17S)-5,14,17-trihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]ethan-1-one
Synonyms Sources
3,11,17,21-Tetrahydroxypregnan-20-one HMDB
3a,11b,17,21-Tetrahydroxy-5a-pregnan-20-one HMDB
3a,11b,17a,21-Tetrahydroxy-5a-pregnan-20-one HMDB
3a,5a-Tetrahydrocortisol HMDB
3a-Allotetrahydrocortisol HMDB
3alpha, 5alpha-Tetrahydrocortisol HMDB
3alpha,5alpha-Tetrahydrocortisol HMDB
5a-Pregnane-3a,11b,17a,21-tetraol-20-one HMDB
5a-Pregnane-3a,11b,17a,21-tetrol-20-one HMDB
5alpha-Tetrahydrocortisol HMDB
a-THF HMDB
Allo-3a-tetrahydrocortisol HMDB
Allo-3alpha-Tetrahydrocortisol HMDB
Allo-Tetrahydrocortisol HMDB
Allopregnane-3a,11b,17a,21-tetrol-20-one HMDB
Allopregnane-3a,11b,21-tetrol-20-one HMDB
Allopregnane-3alpha,11beta,17alpha,21-tetrol-20-one HMDB
Allotetrahydro-Compound f HMDB
Allotetrahydro-Cortisol HMDB
Allotetrahydrocompound f HMDB
Allotetrahydrocortisol HMDB
alpha-THF HMDB
ATHF HMDB
Kendall'S compound c HMDB
Reichstein'S substance C HMDB
Tetrahydro-Allocortisol HMDB
Tetrahydroallocortisol HMDB
Wintersteiner'S compound D HMDB
Manual Xref Database
HMDB0000526 HMDB
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Registry Number Type Source
302-91-0 CAS Registry Number KEGG COMPOUND
Citations Waiting for Citations Types Sources
11085621 PubMed citation Europe PMC
12829005 PubMed citation Europe PMC
14625002 PubMed citation Europe PMC
15149319 PubMed citation Europe PMC
2165347 PubMed citation Europe PMC
2591044 PubMed citation Europe PMC
8641723 PubMed citation Europe PMC
8732999 PubMed citation Europe PMC