CHEBI:87647 - tolonium chloride

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ChEBI Name tolonium chloride
Definition An organic chloride salt having 3-amino-7-(dimethylamino)-2-methylphenothiazin-5-ium (tolonium) as the counterion. It is a blue nuclear counterstain that can be used to demonstrate Nissl substance and is also useful for staining mast cell granules, both in metachromatic and orthochromatic techniques.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C15H16ClN3S
Net Charge 0
Average Mass 305.82600
Monoisotopic Mass 305.075
InChI InChI=1S/C15H16N3S.ClH/c1-9-6-13-15(8-11(9)16)19-14-7-10(18(2)3)4-5-12(14)17-13;/h4-8H,16H2,1-3H3;1H/q+1;/p-1
SMILES [Cl-].CN(C)c1ccc2nc3cc(C)c(N)cc3[s+]c2c1
Roles Classification
Application(s): fluorochrome
A fluorescent dye used to stain biological specimens.
histological dye
A dye used in microscopic or electron microscopic examination of cells and tissues to give contrast and to highlight particular features of interest, such as nuclei and cytoplasm.
diagnostic agent
A substance administered to aid diagnosis of a disease.
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ChEBI Ontology
Outgoing tolonium chloride (CHEBI:87647) has part tolonium (CHEBI:87648)
tolonium chloride (CHEBI:87647) has role diagnostic agent (CHEBI:33295)
tolonium chloride (CHEBI:87647) has role fluorochrome (CHEBI:51217)
tolonium chloride (CHEBI:87647) has role histological dye (CHEBI:77178)
tolonium chloride (CHEBI:87647) is a organic chloride salt (CHEBI:36094)
3-amino-7-(dimethylamino)-2-methylphenothiazin-5-ium chloride
INNs Sources
chlorure de tolonium ChemIDplus
cloruro de tolonio ChemIDplus
tolonii chloridum ChemIDplus
tolonium chloride ChemIDplus
Synonyms Sources
3-Amino-7-(dimethylamino)-2-(methylphenazathionium) chloride ChemIDplus
basic blue 17 ChEBI
Blutene chloride ChemIDplus
C.I. 52040 ChEBI
C.I. 925 ChemIDplus
C.I. Basic Blue 17 ChemIDplus
Dimethyltoluthionine chloride ChemIDplus
toloni chloridum ChemIDplus
Toluidene Blue O Chloride ChemIDplus
Toluidinblau ChemIDplus
toluidine blue ChEBI
toluidine blue O ChEBI
Manual Xref Database
Tolonium_chloride Wikipedia
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Registry Numbers Types Sources
3580048 Reaxys Registry Number Reaxys
92-31-9 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
23884903 PubMed citation Europe PMC
24981641 PubMed citation Europe PMC
25463317 PubMed citation Europe PMC
25670474 PubMed citation Europe PMC
25752750 PubMed citation Europe PMC
25910445 PubMed citation Europe PMC
25972050 PubMed citation Europe PMC
26055566 PubMed citation Europe PMC
Last Modified
25 August 2015