CHEBI:87185 - florfenicol

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name florfenicol
ChEBI ID CHEBI:87185
Definition A carboxamide that is the N-dichloroacetyl derivative of (1R,2S)-2-amino-3-fluoro-1-[4-(methanesulfonyl)phenyl]propan-1-ol. A synthetic veterinary antibiotic that is used for treatment of bovine respiratory disease and foot rot; also used in aquaculture.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Kevin
Supplier Information
Download Molfile XML SDF
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C12H14Cl2FNO4S
Net Charge 0
Average Mass 358.21300
Monoisotopic Mass 357.000
InChI InChI=1S/C12H14Cl2FNO4S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)/t9-,10-/m1/s1
InChIKey AYIRNRDRBQJXIF-NXEZZACHSA-N
SMILES CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl
Roles Classification
Biological Role(s): antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing florfenicol (CHEBI:87185) has functional parent dichloroacetic acid (CHEBI:36386)
florfenicol (CHEBI:87185) has role antimicrobial agent (CHEBI:33281)
florfenicol (CHEBI:87185) is a organochlorine compound (CHEBI:36683)
florfenicol (CHEBI:87185) is a organofluorine compound (CHEBI:37143)
florfenicol (CHEBI:87185) is a secondary alcohol (CHEBI:35681)
florfenicol (CHEBI:87185) is a secondary carboxamide (CHEBI:140325)
florfenicol (CHEBI:87185) is a sulfone (CHEBI:35850)
IUPAC Name
2,2-dichloro-N-{(1R,2S)-3-fluoro-1-hydroxy-1-[4-(methanesulfonyl)phenyl]propan-2-yl}acetamide
INN Source
florfenicol KEGG DRUG
Synonyms Sources
(-)-Florfenicol ChemIDplus
D-threo-2,2-Dichloro-N-(alpha-(fluoromethyl)-beta-hydroxy-p-(methylsulfonyl)phenethyl)acetamide ChemIDplus
Sch 25298 ChemIDplus
Sch-25298 ChemIDplus
Brand Names Sources
Nuflor KEGG DRUG
Nuflor gold ChemIDplus
Manual Xrefs Databases
1777 VSDB
D04194 KEGG DRUG
EP14437 Patent
Florfenicol Wikipedia
LSM-5287 LINCS
US4235892 Patent
View more database links
Registry Numbers Types Sources
4202553 Reaxys Registry Number Reaxys
73231-34-2 CAS Registry Number KEGG DRUG
Citations Waiting for Citations Types Sources
25287575 PubMed citation Europe PMC
25395188 PubMed citation Europe PMC
25567063 PubMed citation Europe PMC
25572306 PubMed citation Europe PMC
25612770 PubMed citation Europe PMC
25614968 PubMed citation Europe PMC
25618189 PubMed citation Europe PMC
25623169 PubMed citation Europe PMC
25675893 PubMed citation Europe PMC
25686865 PubMed citation Europe PMC
25706107 PubMed citation Europe PMC
25723132 PubMed citation Europe PMC
25744433 PubMed citation Europe PMC
25771961 PubMed citation Europe PMC
25827198 PubMed citation Europe PMC
25830490 PubMed citation Europe PMC
25886128 PubMed citation Europe PMC
25886555 PubMed citation Europe PMC
25891823 PubMed citation Europe PMC
25913426 PubMed citation Europe PMC
25973625 PubMed citation Europe PMC
26025252 PubMed citation Europe PMC
26049592 PubMed citation Europe PMC
Last Modified
07 March 2018