CHEBI:85984 - avibactam

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ChEBI Name avibactam
ChEBI ID CHEBI:85984
Definition A member of the class of azabicycloalkanes that is (2S,5R)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide in which the amino hydrogen at position 6 is replaced by a sulfooxy group. Used (in the form of its sodium salt) in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C7H11N3O6S
Net Charge 0
Average Mass 265.24400
Monoisotopic Mass 265.037
InChI InChI=1S/C7H11N3O6S/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15/h4-5H,1-3H2,(H2,8,11)(H,13,14,15)/t4-,5+/m1/s1
InChIKey NDCUAPJVLWFHHB-UHNVWZDZSA-N
SMILES NC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OS(O)(=O)=O
Roles Classification
Biological Role(s): antibacterial drug
A drug used to treat or prevent bacterial infections.
EC 3.5.2.6 (beta-lactamase) inhibitor
An EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor that interferes with the action of beta-lactamase (EC 3.5.2.6).
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
Application(s): antibacterial drug
A drug used to treat or prevent bacterial infections.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing avibactam (CHEBI:85984) has role antibacterial drug (CHEBI:36047)
avibactam (CHEBI:85984) has role antimicrobial agent (CHEBI:33281)
avibactam (CHEBI:85984) has role EC 3.5.2.6 (β-lactamase) inhibitor (CHEBI:35625)
avibactam (CHEBI:85984) is a azabicycloalkane (CHEBI:38295)
avibactam (CHEBI:85984) is a hydroxylamine O-sulfonic acid (CHEBI:38025)
avibactam (CHEBI:85984) is a monocarboxylic acid amide (CHEBI:29347)
avibactam (CHEBI:85984) is a ureas (CHEBI:47857)
avibactam (CHEBI:85984) is conjugate acid of avibactam(1−) (CHEBI:85988)
Incoming avibactam(1−) (CHEBI:85988) is conjugate base of avibactam (CHEBI:85984)
IUPAC Name
(2S,5R)-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide
Synonyms Sources
NXL 104 ChemIDplus
NXL104 ChemIDplus
Manual Xrefs Databases
4946 DrugCentral
Avibactam Wikipedia
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Registry Numbers Types Sources
1192500-31-4 CAS Registry Number ChemIDplus
22542284 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
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Last Modified
22 February 2017