CHEBI:83536 - 1-(3-(trifluoromethyl)phenyl)piperazine

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ChEBI Name 1-(3-(trifluoromethyl)phenyl)piperazine
ChEBI ID CHEBI:83536
Definition A N-arylpiperazine that is piperazine substituted by a 3-(trifluoromethyl)phenyl group at position 1. A serotonergic agonist used as a recreational drug.
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Formula C11H13F3N2
Net Charge 0
Average Mass 230.230
Monoisotopic Mass 230.103
InChI InChI=1S/C11H13F3N2/c12-11(13,14)9-2-1-3-10(8-9)16-6-4-15-5-7-16/h1-3,8,15H,4-7H2
InChIKey KKIMDKMETPPURN-UHFFFAOYSA-N
SMILES C1=C(C(F)(F)F)C=CC=C1N2CCNCC2
Roles Classification
Chemical Role(s): environmental contaminant
Any minor or unwanted substance introduced into the environment that can have undesired effects.
Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): serotonergic agonist
An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
xenobiotic
A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
Application(s): psychotropic drug
A loosely defined grouping of drugs that have effects on psychological function.
serotonergic agonist
An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
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ChEBI Ontology
Outgoing 1-(3-(trifluoromethyl)phenyl)piperazine (CHEBI:83536) has role environmental contaminant (CHEBI:78298)
1-(3-(trifluoromethyl)phenyl)piperazine (CHEBI:83536) has role psychotropic drug (CHEBI:35471)
1-(3-(trifluoromethyl)phenyl)piperazine (CHEBI:83536) has role serotonergic agonist (CHEBI:35941)
1-(3-(trifluoromethyl)phenyl)piperazine (CHEBI:83536) has role xenobiotic (CHEBI:35703)
1-(3-(trifluoromethyl)phenyl)piperazine (CHEBI:83536) is a (trifluoromethyl)benzenes (CHEBI:83565)
1-(3-(trifluoromethyl)phenyl)piperazine (CHEBI:83536) is a N-arylpiperazine (CHEBI:46848)
IUPAC Name
1-[3-(trifluoromethyl)phenyl]piperazine
Synonyms Sources
1-(m-trifluoromethylphenyl)piperazine ChemIDplus
3-trifluoromethylphenylpiperazine ChEBI
N-(α,α,α-trifluoro-3-tolyl)piperazine NIST Chemistry WebBook
TFMPP ChEBI
Manual Xrefs Databases
LSM-24939 LINCS
Trifluoromethylphenylpiperazine Wikipedia
View more database links
Registry Numbers Types Sources
15532-75-9 CAS Registry Number NIST Chemistry WebBook
15532-75-9 CAS Registry Number ChemIDplus
614217 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
23890650 PubMed citation Europe PMC
24547667 PubMed citation Europe PMC
24810679 PubMed citation Europe PMC
24968061 PubMed citation Europe PMC
Last Modified
06 July 2016