CHEBI:83499 - climbazole

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ChEBI Name climbazole
ChEBI ID CHEBI:83499
Definition A racemate composed of equimolar amounts of (R)- and (S)-climbazole. It is a topically applied antifungal agent used to treat human fungal skin infections.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C15H17ClN2O2
Net Charge 0
Average Mass 292.761
Monoisotopic Mass 292.098
Roles Classification
Chemical Role(s): environmental contaminant
Any minor or unwanted substance introduced into the environment that can have undesired effects.
Biological Role(s): xenobiotic
A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
(via imidazole antifungal drug )
(via conazole antifungal drug )
antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
(via imidazole antifungal agent )
(via conazole antifungal agent )
ergosterol biosynthesis inhibitor
Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol.
(via conazole antifungal agent )
Application(s): antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
(via imidazole antifungal drug )
(via conazole antifungal drug )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing climbazole (CHEBI:83499) has part (R)-climbazole (CHEBI:83720)
climbazole (CHEBI:83499) has part (S)-climbazole (CHEBI:83722)
climbazole (CHEBI:83499) has role environmental contaminant (CHEBI:78298)
climbazole (CHEBI:83499) has role xenobiotic (CHEBI:35703)
climbazole (CHEBI:83499) is a conazole antifungal drug (CHEBI:87071)
climbazole (CHEBI:83499) is a imidazole antifungal drug (CHEBI:87069)
climbazole (CHEBI:83499) is a racemate (CHEBI:60911)
IUPAC Name
rac-1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one
INNs Sources
climbazol ChemIDplus
climbazole WHO MedNet
climbazole WHO MedNet
Climbazolum ChemIDplus
Synonyms Sources
(RS)-1-(4-chlorophenoxy)-1-imidazol-1-yl-3,3-dimethylbutan-2-one Alan Wood's Pesticides
1-(p-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethyl -2-butanone ChEBI
climbazol ChEBI
Manual Xrefs Databases
climbazole Alan Wood's Pesticides
Climbazole Wikipedia
DE102012203240 Patent
View more database links
Registry Numbers Types Sources
38083-17-9 CAS Registry Number ChemIDplus
618020 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
11552297 PubMed citation Europe PMC
11824557 PubMed citation Europe PMC
18950734 PubMed citation Europe PMC
21272039 PubMed citation Europe PMC
23542433 PubMed citation Europe PMC
23958691 PubMed citation Europe PMC
23982925 PubMed citation Europe PMC
24811958 PubMed citation Europe PMC
25794970 PubMed citation Europe PMC
27378240 PubMed citation Europe PMC
Last Modified
22 February 2017