CHEBI:83353 - eliglustat tartrate

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ChEBI Name eliglustat tartrate
Definition A tartrate that is the hemitartrate salt of eliglustat. A ceramide glucosyltransferase inhibitor used (as its tartrate salt) for treatment of Gaucher's disease.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C50H78N4O14
Net Charge 0
Average Mass 959.17270
Monoisotopic Mass 958.55145
InChI InChI=1S/2C23H36N2O4.C4H6O6/c2*1-2-3-4-5-6-9-22(26)24-19(17-25-12-7-8-13-25)23(27)18-10-11-20-21(16-18)29-15-14-28-20;5-1(3(7)8)2(6)4(9)10/h2*10-11,16,19,23,27H,2-9,12-15,17H2,1H3,(H,24,26);1-2,5-6H,(H,7,8)(H,9,10)/t2*19-,23-;1-,2-/m111/s1
SMILES O[C@H]([C@@H](O)C(O)=O)C(O)=O.CCCCCCCC(=O)N[C@H](CN1CCCC1)[C@H](O)c1ccc2OCCOc2c1.CCCCCCCC(=O)N[C@H](CN1CCCC1)[C@H](O)c1ccc2OCCOc2c1
Roles Classification
Biological Role(s): EC (ceramide glucosyltransferase) inhibitor
An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the activity of ceramide glucosyltransferase (EC
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ChEBI Ontology
Outgoing eliglustat tartrate (CHEBI:83353) has part eliglustat(1+) (CHEBI:83355)
eliglustat tartrate (CHEBI:83353) has role EC (ceramide glucosyltransferase) inhibitor (CHEBI:50382)
eliglustat tartrate (CHEBI:83353) is a tartrate salt (CHEBI:50562)
bis{1-[(2R,3R)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-hydroxy-2-(octanoylamino)propyl]pyrrolidinium} (2R,3R)-2,3-dihydroxysuccinate
bis{N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl]octanamide} (2R,3R)-2,3-dihydroxysuccinic acid
Synonyms Sources
eliglustat hemitartrate ChEBI
eliglustat L-tartrate ChEBI
Genz-112638 ChemIDplus
Brand Name Source
Cerdelga ChemIDplus
Manual Xrefs Databases
Eliglustat Wikipedia
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Registry Numbers Types Sources
21475296 Reaxys Registry Number Reaxys
928659-70-5 CAS Registry Number KEGG DRUG
928659-70-5 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
20 October 2014