CHEBI:82625 - Trolox

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ChEBI Name Trolox
ChEBI ID CHEBI:82625
Definition A chromanol that is 6-hydroxychromane which is substituted by a carboxy group at position 2 and by methyl groups at positions 2, 5, 7, and 8. A cell-permeable, water-soluble analogue of vitamin E, it is used as a standard for measuring the antioxidant capacity of complex mixtures.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C14H18O4
Net Charge 0
Average Mass 250.29030
Monoisotopic Mass 250.121
InChI InChI=1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)
InChIKey GLEVLJDDWXEYCO-UHFFFAOYSA-N
SMILES Cc1c(C)c2OC(C)(CCc2c(C)c1O)C(O)=O
Roles Classification
Chemical Role(s): antioxidant
A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
radical scavenger
A role played by a substance that can react readily with, and thereby eliminate, radicals.
Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
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ChEBI Ontology
Outgoing Trolox (CHEBI:82625) has role antioxidant (CHEBI:22586)
Trolox (CHEBI:82625) has role radical scavenger (CHEBI:48578)
Trolox (CHEBI:82625) is a chromanol (CHEBI:23229)
Trolox (CHEBI:82625) is a monocarboxylic acid (CHEBI:25384)
Trolox (CHEBI:82625) is a phenols (CHEBI:33853)
IUPAC Name
6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid
Synonym Source
3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid ChemIDplus
Brand Names Sources
Trolox ChemIDplus
Trolox C ChemIDplus
Manual Xrefs Databases
HMDB0038804 HMDB
LSM-4987 LINCS
Trolox Wikipedia
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Registry Numbers Types Sources
5052542 Reaxys Registry Number Reaxys
53188-07-1 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
25 February 2016