CHEBI:8247 - pirenzepine

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ChEBI Name pirenzepine
ChEBI ID CHEBI:8247
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C19H21N5O2
Net Charge 0
Average Mass 351.40230
Monoisotopic Mass 351.170
InChI InChI=1S/C19H21N5O2/c1-22-9-11-23(12-10-22)13-17(25)24-16-7-3-2-5-14(16)19(26)21-15-6-4-8-20-18(15)24/h2-8H,9-13H2,1H3,(H,21,26)
InChIKey RMHMFHUVIITRHF-UHFFFAOYSA-N
SMILES CN1CCN(CC1)CC(=O)N1c2ccccc2C(=O)Nc2cccnc12
Roles Classification
Biological Role(s): muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
Application(s): anti-ulcer drug
One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract.
muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
antispasmodic drug
A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing pirenzepine (CHEBI:8247) has role anti-ulcer drug (CHEBI:49201)
pirenzepine (CHEBI:8247) has role antispasmodic drug (CHEBI:53784)
pirenzepine (CHEBI:8247) has role muscarinic antagonist (CHEBI:48876)
pirenzepine (CHEBI:8247) is a pyridobenzodiazepine (CHEBI:71329)
Incoming pirenzepine hydrochloride (CHEBI:32014) has part pirenzepine (CHEBI:8247)
IUPAC Name
11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
INNs Sources
pirenzepina ChemIDplus
pirenzépine ChEBI
pirenzepine ChemIDplus
pirenzepinum ChemIDplus
Synonym Source
11-((4-Methyl-1-piperazinyl)acetyl)-5,11-dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one ChemIDplus
Manual Xrefs Databases
2200 DrugCentral
C07508 KEGG COMPOUND
D08389 KEGG DRUG
DB00670 DrugBank
FR1505795 Patent
LSM-4001 LINCS
View more database links
Registry Numbers Types Sources
28797-61-7 CAS Registry Number ChemIDplus
628987 Beilstein Registry Number Beilstein
Last Modified
22 February 2017