CHEBI:79091 - EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor

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ChEBI Name EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
ChEBI ID CHEBI:79091
Definition An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of mitogen-activated protein kinase (EC 2.7.11.24).
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:75997
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ChEBI Ontology
Outgoing EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091) is a EC 2.7.11.* (protein-serine/threonine kinase) inhibitor (CHEBI:76812)
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091) is a protein kinase inhibitor (CHEBI:37699)
Incoming 1-(3-tert-butyl-1-methylpyrazol-5-yl)-3-(4-chlorophenyl)urea (CHEBI:47249) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
2-(2-amino-3-methoxyphenyl)chromen-4-one (CHEBI:77954) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
3-fluoro-5-morpholin-4-yl-N-[1-(2-pyridin-4-ylethyl)-1H-indol-6-yl]benzamide (CHEBI:46552) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
4-methyl-N-[3-(morpholin-4-yl)phenyl]-3-[3-(piperidin-4-yl)-1,2-benzoxazol-6-yl]benzamide (CHEBI:90542) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
4-phenoxy-N-(pyridin-2-ylmethyl)benzamide (CHEBI:41135) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
9-(4-hydroxyphenyl)-2,7-phenanthroline (CHEBI:40444) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-2-fluorobenzamide (CHEBI:40300) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide (CHEBI:49627) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide (CHEBI:90544) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
N-cyclopropyl-3-{4-[(cyclopropylmethyl)carbamoyl]phenyl}-4-methylbenzamide (CHEBI:90527) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydropyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide (CHEBI:82714) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
auraptene (CHEBI:134355) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
binimetinib (CHEBI:145371) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
cercosporamide (CHEBI:78696) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
CH5126766 (CHEBI:78825) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
cobimetinib (CHEBI:90851) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
cobimetinib fumarate (CHEBI:90853) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
doramapimod (CHEBI:40953) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
G-573 (CHEBI:83404) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
hypothemycin (CHEBI:83275) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
pamapimod (CHEBI:90685) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
PH 797804 (CHEBI:82715) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
RO4927350 (CHEBI:132984) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
SB 203580 (CHEBI:90705) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
SB-202190 (CHEBI:79090) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
SB-239063 (CHEBI:90681) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
SB-245391 (CHEBI:144676) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
SB-284851-BT (CHEBI:144677) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
SB220025 (CHEBI:82713) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
selumetinib (CHEBI:90227) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
talmapimod (CHEBI:90683) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
trametinib (CHEBI:75998) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
trametinib dimethyl sulfoxide (CHEBI:75991) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
U0126 (CHEBI:90693) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
U0126.EtOH (CHEBI:90692) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
VX-745 (CHEBI:90528) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
c-Jun N-terminal kinase inhibitor (CHEBI:90172) is a EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
Synonyms Sources
ATP:protein phosphotransferase (MAPKK-activated) inhibitor ChEBI
ATP:protein phosphotransferase (MAPKK-activated) inhibitors ChEBI
c-Jun N-terminal kinase inhibitor ChEBI
c-Jun N-terminal kinase inhibitors ChEBI
Dp38 inhibitor ChEBI
Dp38 inhibitors ChEBI
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitors ChEBI
EC 2.7.11.24 inhibitor ChEBI
EC 2.7.11.24 inhibitors ChEBI
ERK inhibitor ChEBI
ERK inhibitors ChEBI
ERK1 inhibitor ChEBI
ERK1 inhibitors ChEBI
ERK2 inhibitor ChEBI
ERK2 inhibitors ChEBI
extracellular signal-regulated kinase inhibitor ChEBI
extracellular signal-regulated kinase inhibitors ChEBI
JNK inhibitor ChEBI
JNK inhibitors ChEBI
JNK3α1 inhibitor ChEBI
JNK3α1 inhibitors ChEBI
LeMPK3 inhibitor ChEBI
LeMPK3 inhibitors ChEBI
MAP kinase inhibitor ChEBI
MAP kinase inhibitors ChEBI
MAP-2 kinase inhibitor ChEBI
MAP-2 kinase inhibitors ChEBI
MAPK inhibitor ChEBI
MAPK inhibitors ChEBI
MBP kinase I inhibitor ChEBI
MBP kinase I inhibitors ChEBI
MBP kinase II inhibitor ChEBI
MBP kinase II inhibitors ChEBI
MEK inhibitor ChEBI
MEK inhibitors ChEBI
microtubule-associated protein 2 kinase inhibitor ChEBI
microtubule-associated protein 2 kinase inhibitors ChEBI
microtubule-associated protein kinase inhibitor ChEBI
microtubule-associated protein kinase inhibitors ChEBI
mitogen-activated protein kinase (EC 2.7.11.24) inhibitor ChEBI
mitogen-activated protein kinase (EC 2.7.11.24) inhibitors ChEBI
mitogen-activated protein kinase inhibitor ChEBI
mitogen-activated protein kinase inhibitors ChEBI
mitogen-activated protein kinase inhibitors ChEBI
myelin basic protein kinase inhibitor ChEBI
myelin basic protein kinase inhibitors ChEBI
p38-2 inhibitor ChEBI
p38-2 inhibitors ChEBI
p38δ inhibitor ChEBI
p38δ inhibitors ChEBI
p42 mitogen-activated protein kinase inhibitor ChEBI
p42 mitogen-activated protein kinase inhibitors ChEBI
p42mapk inhibitor ChEBI
p42mapk inhibitors ChEBI
p44mpk inhibitor ChEBI
p44mpk inhibitors ChEBI
PMK-1 inhibitor ChEBI
PMK-1 inhibitors ChEBI
PMK-2 inhibitor ChEBI
PMK-2 inhibitors ChEBI
PMK-3 inhibitor ChEBI
PMK-3 inhibitors ChEBI
pp42 inhibitor ChEBI
pp42 inhibitors ChEBI
pp44mapk inhibitor ChEBI
pp44mapk inhibitors ChEBI
SAPK inhibitor ChEBI
SAPK inhibitors ChEBI
STK26 inhibitor ChEBI
STK26 inhibitors ChEBI
stress-activated protein kinase inhibitor ChEBI
stress-activated protein kinase inhibitors ChEBI
Manual Xrefs Databases
MEK_inhibitor Wikipedia
Mitogen-activated_protein_kinase Wikipedia
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Last Modified
14 November 2019