CHEBI:7822 - oxaprozin

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ChEBI Name oxaprozin
ChEBI ID CHEBI:7822
Definition A monocarboxylic acid that is a propionic acid derivative having a 4,5-diphenyl-1,3-oxazol-2-yl substituent at position 3. It is non-steroidal anti-inflammatory drug commonly used to relieve the pain and inflammatory responses associated with osteoarthritis and rheumatoid arthritis.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C18H15NO3
Net Charge 0
Average Mass 293.31660
Monoisotopic Mass 293.105
InChI InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21)
InChIKey OFPXSFXSNFPTHF-UHFFFAOYSA-N
SMILES OC(=O)CCc1nc(-c2ccccc2)c(o1)-c1ccccc1
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): analgesic
An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
Application(s): non-steroidal anti-inflammatory drug
An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
analgesic
An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
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ChEBI Ontology
Outgoing oxaprozin (CHEBI:7822) has functional parent propionic acid (CHEBI:30768)
oxaprozin (CHEBI:7822) has role analgesic (CHEBI:35480)
oxaprozin (CHEBI:7822) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
oxaprozin (CHEBI:7822) is a 1,3-oxazoles (CHEBI:46812)
oxaprozin (CHEBI:7822) is a monocarboxylic acid (CHEBI:25384)
IUPAC Name
3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid
INNs Sources
oxaprozin ChemIDplus
oxaprozina ChemIDplus
oxaprozine ChemIDplus
oxaprozinum ChemIDplus
Brand Names Sources
Danoprox ChEBI
Daypro KEGG DRUG
Dayrun ChEBI
Deflam ChEBI
Duraprox ChEBI
Walix ChEBI
Manual Xrefs Databases
2013 DrugCentral
C07356 KEGG COMPOUND
D00463 KEGG DRUG
DB00991 DrugBank
FR2001036 Patent
GB1206403 Patent
HMDB0015126 HMDB
LSM-2553 LINCS
Oxaprozin Wikipedia
US3578671 Patent
WO2007082542 Patent
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Registry Numbers Types Sources
1083168 Reaxys Registry Number Reaxys
21256-18-8 CAS Registry Number KEGG COMPOUND
21256-18-8 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
22 February 2017