CHEBI:77954 - 2-(2-amino-3-methoxyphenyl)chromen-4-one

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ChEBI Name 2-(2-amino-3-methoxyphenyl)chromen-4-one
Definition A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C16H13NO3
Net Charge 0
Average Mass 267.27930
Monoisotopic Mass 267.08954
InChI InChI=1S/C16H13NO3/c1-19-14-8-4-6-11(16(14)17)15-9-12(18)10-5-2-3-7-13(10)20-15/h2-9H,17H2,1H3
SMILES COc1cccc(c1N)-c1cc(=O)c2ccccc2o1
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): EC (mitogen-activated protein kinase) inhibitor
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of mitogen-activated protein kinase (EC
Application(s): geroprotector
Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing 2-(2-amino-3-methoxyphenyl)chromen-4-one (CHEBI:77954) has role EC (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
2-(2-amino-3-methoxyphenyl)chromen-4-one (CHEBI:77954) has role geroprotector (CHEBI:176497)
2-(2-amino-3-methoxyphenyl)chromen-4-one (CHEBI:77954) is a aromatic amine (CHEBI:33860)
2-(2-amino-3-methoxyphenyl)chromen-4-one (CHEBI:77954) is a monomethoxyflavone (CHEBI:25401)
Synonyms Sources
2'-amino-3'-methoxyflavone ChEBI
2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one ChemIDplus
PD 98,059 ChemIDplus
PD 98059 ChemIDplus
PD-98059 ChemIDplus
PD98059 ChemIDplus
Manual Xrefs Databases
4551 ChemSpider
HMDB0244751 HMDB
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Registry Numbers Types Sources
167869-21-8 CAS Registry Number ChemIDplus
8148190 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
11804618 PubMed citation Europe PMC
12680846 PubMed citation Europe PMC
22363408 PubMed citation Europe PMC
24601228 PubMed citation Europe PMC
34071138 PubMed citation Europe PMC
34252520 PubMed citation Europe PMC
9633509 PubMed citation Europe PMC
9742931 PubMed citation Europe PMC
9786874 PubMed citation Europe PMC
Last Modified
27 October 2021