CHEBI:77942 - tavaborole

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ChEBI Name tavaborole
Definition A member of the class of benzoxaboroles that is 1,3-dihydro-1-hydroxy-2,1-benzoxaborole substituted at position 5 by a fluoro group. A topical antifungal agent used for the treatment of onychomycosis (fungal infection of the toenails and fingernails).
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C7H6BFO2
Net Charge 0
Average Mass 151.93100
Monoisotopic Mass 152.04449
InChI InChI=1S/C7H6BFO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,10H,4H2
SMILES OB1OCc2cc(F)ccc12
Roles Classification
Biological Role(s): antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
protein synthesis inhibitor
A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein.
EC (leucine--tRNA ligase) inhibitor
An EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor that inhibits the action of leucinetRNA synthetase (EC
View more via ChEBI Ontology
ChEBI Ontology
Outgoing tavaborole (CHEBI:77942) has role antifungal agent (CHEBI:35718)
tavaborole (CHEBI:77942) has role EC (leucine—tRNA ligase) inhibitor (CHEBI:77953)
tavaborole (CHEBI:77942) has role protein synthesis inhibitor (CHEBI:48001)
tavaborole (CHEBI:77942) is a benzoxaborole (CHEBI:78240)
tavaborole (CHEBI:77942) is a organofluorine compound (CHEBI:37143)
Synonyms Sources
5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole ChemIDplus
AN 2690 ChemIDplus
AN-2690 ChemIDplus
AN2690 ChemIDplus
Manual Xrefs Databases
4877 DrugCentral
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Registry Numbers Types Sources
10657796 Reaxys Registry Number Reaxys
174671-46-6 CAS Registry Number KEGG DRUG
174671-46-6 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
22 February 2017