CHEBI:77942 - tavaborole

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ChEBI Name tavaborole
ChEBI ID CHEBI:77942
Definition A member of the class of benzoxaboroles that is 1,3-dihydro-1-hydroxy-2,1-benzoxaborole substituted at position 5 by a fluoro group. A topical antifungal agent used for the treatment of onychomycosis (fungal infection of the toenails and fingernails).
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C7H6BFO2
Net Charge 0
Average Mass 151.93100
Monoisotopic Mass 152.04449
InChI InChI=1S/C7H6BFO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,10H,4H2
InChIKey LFQDNHWZDQTITF-UHFFFAOYSA-N
SMILES OB1OCc2cc(F)ccc12
Roles Classification
Biological Role(s): antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
protein synthesis inhibitor
A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein.
EC 6.1.1.4 (leucine--tRNA ligase) inhibitor
An EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor that inhibits the action of leucinetRNA synthetase (EC 6.1.1.4).
View more via ChEBI Ontology
ChEBI Ontology
Outgoing tavaborole (CHEBI:77942) has role antifungal agent (CHEBI:35718)
tavaborole (CHEBI:77942) has role EC 6.1.1.4 (leucine—tRNA ligase) inhibitor (CHEBI:77953)
tavaborole (CHEBI:77942) has role protein synthesis inhibitor (CHEBI:48001)
tavaborole (CHEBI:77942) is a benzoxaborole (CHEBI:78240)
tavaborole (CHEBI:77942) is a organofluorine compound (CHEBI:37143)
IUPAC Name
5-fluoro-2,1-benzoxaborol-1(3H)-ol
Synonyms Sources
5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole ChemIDplus
AN 2690 ChemIDplus
AN-2690 ChemIDplus
AN2690 ChemIDplus
Manual Xrefs Databases
4877 DrugCentral
D10169 KEGG DRUG
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Registry Numbers Types Sources
10657796 Reaxys Registry Number Reaxys
174671-46-6 CAS Registry Number KEGG DRUG
174671-46-6 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
16854048 PubMed citation Europe PMC
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Last Modified
22 February 2017