CHEBI:77573 - tosufloxacin

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ChEBI Name tosufloxacin
Definition A racemate comprising equimolar amounts of (R)- and (S)-tosufloxacin.
Stars This entity has been manually annotated by the ChEBI Team.
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Roles Classification
Biological Role(s): antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
(via quinolone antibiotic )
(via heterocyclic antibiotic )
DNA synthesis inhibitor
Any substance that inhibits the synthesis of DNA.
topoisomerase IV inhibitor
A topoisomerase inhibitor that inhibits DNA topoisomerase IV, which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.
hepatotoxic agent
A role played by a chemical compound exihibiting itself through the ability to induce damage to the liver in animals.
Application(s): antiinfective agent
A substance used in the prophylaxis or therapy of infectious diseases.
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ChEBI Ontology
Outgoing tosufloxacin (CHEBI:77573) has part (R)-tosufloxacin (CHEBI:77584)
tosufloxacin (CHEBI:77573) has part (S)-tosufloxacin (CHEBI:77582)
tosufloxacin (CHEBI:77573) has role antiinfective agent (CHEBI:35441)
tosufloxacin (CHEBI:77573) has role antimicrobial agent (CHEBI:33281)
tosufloxacin (CHEBI:77573) has role DNA synthesis inhibitor (CHEBI:59517)
tosufloxacin (CHEBI:77573) has role hepatotoxic agent (CHEBI:50908)
tosufloxacin (CHEBI:77573) has role topoisomerase IV inhibitor (CHEBI:53559)
tosufloxacin (CHEBI:77573) is a quinolone antibiotic (CHEBI:86324)
tosufloxacin (CHEBI:77573) is a racemate (CHEBI:60911)
tosufloxacin (CHEBI:77573) is conjugate base of tosufloxacin(1+) (CHEBI:77586)
Incoming tosufloxacin(1+) (CHEBI:77586) is conjugate acid of tosufloxacin (CHEBI:77573)
rac-7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
INNs Sources
tosufloxacin ChemIDplus
tosufloxacin WHO MedNet
tosufloxacino WHO MedNet
tosufloxacinum WHO MedNet
Synonyms Sources
(±)-tosufloxacin ChEBI
(RS)-tosufloxacin ChEBI
A 61827 ChemIDplus
Abbott 61827 ChemIDplus
Abbott-61827 ChemIDplus
rac-tosufloxacin ChEBI
racemic tosufloxacin ChEBI
Manual Xrefs Databases
Tosufloxacin Wikipedia
View more database links
Registry Numbers Types Sources
100490-36-6 CAS Registry Number ChemIDplus
100490-36-6 CAS Registry Number KEGG DRUG
4913117 Reaxys Registry Number Reaxys
4913117 Beilstein Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
1380905 PubMed citation Europe PMC
22346290 PubMed citation Europe PMC
22428211 PubMed citation Europe PMC
22978686 PubMed citation Europe PMC
23173293 PubMed citation Europe PMC
23459497 PubMed citation Europe PMC
2745259 PubMed citation Europe PMC
Last Modified
22 February 2017