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CHEBI:76249 - miroprofen

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ChEBI Name miroprofen
ChEBI ID CHEBI:76249
Definition A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(imidazo[1,2-a]pyridin-2-yl)phenyl group. A non-steroidal anti-inflammatory drug that also exhibits analgesic, antipyretic and platelet aggregation inhibition properties.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C16H14N2O2
Net Charge 0
Average Mass 266.29460
Monoisotopic Mass 266.106
InChI InChI=1S/C16H14N2O2/c1-11(16(19)20)12-5-7-13(8-6-12)14-10-18-9-3-2-4-15(18)17-14/h2-11H,1H3,(H,19,20)
InChIKey OJGQFYYLKNCIJD-UHFFFAOYSA-N
SMILES CC(C(O)=O)c1ccc(cc1)-c1cn2ccccc2n1
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Application(s): non-steroidal anti-inflammatory drug
An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
platelet aggregation inhibitor
A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
antipyretic
A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing miroprofen (CHEBI:76249) has functional parent propionic acid (CHEBI:30768)
miroprofen (CHEBI:76249) has role antipyretic (CHEBI:35493)
miroprofen (CHEBI:76249) has role non-narcotic analgesic (CHEBI:35481)
miroprofen (CHEBI:76249) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
miroprofen (CHEBI:76249) has role platelet aggregation inhibitor (CHEBI:50427)
miroprofen (CHEBI:76249) is a imidazopyridine (CHEBI:46908)
miroprofen (CHEBI:76249) is a monocarboxylic acid (CHEBI:25384)
IUPAC Name
2-[4-(imidazo[1,2-a]pyridin-2-yl)phenyl]propanoic acid
INNs Sources
miroprofen ChemIDplus
miroprofene ChemIDplus
miroprofeno ChemIDplus
miroprofenum ChemIDplus
Synonyms Sources
2-(p-(2-Imidazo(1,2-a)pyridyl)phenyl)propionic acid ChemIDplus
4-Imidazo(1,2-a)pyridin-2-yl-alpha-methylbenzeneacetic acid ChemIDplus
p-Imidazo(1,2-a)pyridin-2-ylhydratropic acid ChemIDplus
Y 9213 ChemIDplus
Y-9213 ChemIDplus
Database Link Database
Miroprofen Wikipedia
View more database links
Registry Numbers Types Sources
55843-86-2 CAS Registry Number ChemIDplus
888858 Reaxys Registry Number Reaxys
888858 Beilstein Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
315230 PubMed citation Europe PMC
398281 PubMed citation Europe PMC
459158 PubMed citation Europe PMC
6603669 PubMed citation Europe PMC
6811679 PubMed citation Europe PMC
7020126 PubMed citation Europe PMC
702946 PubMed citation Europe PMC
7045328 PubMed citation Europe PMC
7196760 PubMed citation Europe PMC
871368 PubMed citation Europe PMC
Last Modified
05 December 2013