CHEBI:76130 - difenpiramide

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ChEBI Name difenpiramide
Definition A monocarboxylic acid amide obtained by formal condensation of the carboxy group from biphenyl-4-ylacetic acid with the amino group of 2-aminopyridine. Used for treatment of rheumatoid arthritis.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C19H16N2O
Net Charge 0
Average Mass 288.344
Monoisotopic Mass 288.12626
InChI InChI=1S/C19H16N2O/c22-19(21-18-8-4-5-13-20-18)14-15-9-11-17(12-10-15)16-6-2-1-3-7-16/h1-13H,14H2,(H,20,21,22)
Roles Classification
Biological Role(s): non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Application(s): non-steroidal anti-inflammatory drug
An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.
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ChEBI Ontology
Outgoing difenpiramide (CHEBI:76130) has functional parent biphenyl-4-ylacetic acid (CHEBI:31597)
difenpiramide (CHEBI:76130) has role antipyretic (CHEBI:35493)
difenpiramide (CHEBI:76130) has role non-narcotic analgesic (CHEBI:35481)
difenpiramide (CHEBI:76130) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
difenpiramide (CHEBI:76130) is a biphenyls (CHEBI:22888)
difenpiramide (CHEBI:76130) is a monocarboxylic acid amide (CHEBI:29347)
difenpiramide (CHEBI:76130) is a pyridines (CHEBI:26421)
Synonyms Sources
2-Biphenylyl-N-pyridylacetamide ChemIDplus
Diphenpyramide ChemIDplus
N-2-Pyridinyl-(1,1'-biphenyl)-4-acetamide ChemIDplus
N-Pyridin-2-yl(1,1'-biphenyl)-4-acetamide ChemIDplus
Manual Xrefs Databases
919 DrugCentral
Difenpiramide Wikipedia
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Registry Numbers Types Sources
483768 Reaxys Registry Number Reaxys
483768 Beilstein Registry Number ChemIDplus
51484-40-3 CAS Registry Number KEGG COMPOUND
51484-40-3 CAS Registry Number KEGG DRUG
51484-40-3 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
22 February 2017