CHEBI:76023 - thioflavine T

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ChEBI Name thioflavine T
ChEBI ID CHEBI:76023
Definition An organic chloride salt having 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium as the counterion. It is widely used to visualise and quantify the presence of amyloids, both in vitro and in vivo.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Margaret Duesbury
Secondary ChEBI IDs CHEBI:88013
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Formula C17H19ClN2S
Net Charge 0
Average Mass 318.866
Monoisotopic Mass 318.096
InChI InChI=1S/C17H19N2S.ClH/c1-12-5-10-15-16(11-12)20-17(19(15)4)13-6-8-14(9-7-13)18(2)3;/h5-11H,1-4H3;1H/q+1;/p-1
InChIKey JADVWWSKYZXRGX-UHFFFAOYSA-M
SMILES C=1(C=2C=CC(N(C)C)=CC2)SC=3C=C(C)C=CC3[N+]1C.[Cl-]
Roles Classification
Application(s): fluorochrome
A fluorescent dye used to stain biological specimens.
histological dye
A dye used in microscopic or electron microscopic examination of cells and tissues to give contrast and to highlight particular features of interest, such as nuclei and cytoplasm.
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ChEBI Ontology
Outgoing thioflavine T (CHEBI:76023) has part thioflavin T cation (CHEBI:76034)
thioflavine T (CHEBI:76023) has role fluorochrome (CHEBI:51217)
thioflavine T (CHEBI:76023) has role histological dye (CHEBI:77178)
thioflavine T (CHEBI:76023) is a organic chloride salt (CHEBI:36094)
IUPAC Name
2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium chloride
Synonyms Sources
2-(4-(Dimethylamino)phenyl)-3,6-dimethylbenzothiazolium chloride ChemIDplus
basic yellow 1 ChEBI
C.I. 49005 ChEBI
C.I. Basic Yellow 1 ChemIDplus
Thioflavin T ChemIDplus
ThT SUBMITTER
Manual Xrefs Databases
Thioflavin_T Wikipedia
WO2006006172 Patent
WO2007011834 Patent
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Registry Numbers Types Sources
2390-54-7 CAS Registry Number ChemIDplus
3922452 Reaxys Registry Number Reaxys
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Last Modified
24 September 2015