CHEBI:75405 - tyrphostin AG 825

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ChEBI Name tyrphostin AG 825
Definition An organic sulfide that consists of 1,3-benzothiazole-2-thiol in which the hydrogen attached to the sulfur atom is replaced by a 5-[(1E)-3-amino-2-cyano-3-oxoprop-1-en-1-yl]-2-hydroxy-3-methoxybenzyl group. It acts as an epidermal growth factor receptor antagonist.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C19H15N3O3S2
Net Charge 0
Average Mass 397.474
Monoisotopic Mass 397.05548
InChI InChI=1S/C19H15N3O3S2/c1-25-15-8-11(6-12(9-20)18(21)24)7-13(17(15)23)10-26-19-22-14-4-2-3-5-16(14)27-19/h2-8,23H,10H2,1H3,(H2,21,24)/b12-6+
Roles Classification
Biological Role(s): epidermal growth factor receptor antagonist
An antagonist at the epidermal growth factor receptor.
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ChEBI Ontology
Outgoing tyrphostin AG 825 (CHEBI:75405) has functional parent 1,3-benzothiazole-2-thiol (CHEBI:34292)
tyrphostin AG 825 (CHEBI:75405) has role epidermal growth factor receptor antagonist (CHEBI:74440)
tyrphostin AG 825 (CHEBI:75405) is a aromatic ether (CHEBI:35618)
tyrphostin AG 825 (CHEBI:75405) is a benzothiazoles (CHEBI:37947)
tyrphostin AG 825 (CHEBI:75405) is a enamide (CHEBI:51751)
tyrphostin AG 825 (CHEBI:75405) is a nitrile (CHEBI:18379)
tyrphostin AG 825 (CHEBI:75405) is a organic sulfide (CHEBI:16385)
tyrphostin AG 825 (CHEBI:75405) is a phenols (CHEBI:33853)
tyrphostin AG 825 (CHEBI:75405) is a primary carboxamide (CHEBI:140324)
Registry Number Type Source
14612999 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
20049896 PubMed citation Europe PMC
9735325 PubMed citation Europe PMC
Last Modified
07 March 2018