CHEBI:75307 - BW B70C

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ChEBI Name BW B70C
Definition A hydroxamic acid that is urea in which both the hydrogens attached to one of the nitrogens are replaced by a hydroxy and a (1E)-1-[3-(4-fluorophenoxy)phenyl]but-1-en-3-yl group. A selective inhibitor of arachidonate 5-lipoxygenase, it can be used for the treatment of asthma.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C17H17FN2O3
Net Charge 0
Average Mass 316.32690
Monoisotopic Mass 316.12232
InChI InChI=1S/C17H17FN2O3/c1-12(20(22)17(19)21)5-6-13-3-2-4-16(11-13)23-15-9-7-14(18)8-10-15/h2-12,22H,1H3,(H2,19,21)/b6-5+
SMILES CC(\C=C\c1cccc(Oc2ccc(F)cc2)c1)N(O)C(N)=O
Roles Classification
Biological Role(s): EC (arachidonate 5-lipoxygenase) inhibitor
A lipoxygenase inhibitor that interferes with the action of arachidonate 5-lipoxygenase (EC
View more via ChEBI Ontology
ChEBI Ontology
Outgoing BW B70C (CHEBI:75307) has role EC (arachidonate 5-lipoxygenase) inhibitor (CHEBI:64964)
BW B70C (CHEBI:75307) is a aromatic ether (CHEBI:35618)
BW B70C (CHEBI:75307) is a hydroxamic acid (CHEBI:24650)
BW B70C (CHEBI:75307) is a organofluorine compound (CHEBI:37143)
BW B70C (CHEBI:75307) is a ureas (CHEBI:47857)
Synonyms Sources
(E)-N-(3-(3-(4-Fluorophenoxy)phenyl)-1-(R,S)-methylprop-2-enyl)-N-hydroxyurea ChEBI
70C ChemIDplus
Registry Numbers Types Sources
134470-38-5 CAS Registry Number ChemIDplus
8853259 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
11094642 PubMed citation Europe PMC
1375522 PubMed citation Europe PMC
16689995 PubMed citation Europe PMC
1793063 PubMed citation Europe PMC
19826192 PubMed citation Europe PMC
7809921 PubMed citation Europe PMC
8480540 PubMed citation Europe PMC
8535100 PubMed citation Europe PMC
Last Modified
23 August 2013