CHEBI:74895 - 223RaCl2

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ChEBI Name 223RaCl2
ChEBI ID CHEBI:74895
ChEBI ASCII Name (223)RaCl2
Definition A radium molecular entity with formula 223RaCl2. Used as as a radiotherapeutic agent for the treatment of patients with castration-resistant prostate cancer, symptomatic bone metastases and no known visceral metastatic disease. An alpha-emitter, radium-223 has a half-life of 11.4 days.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula Cl2Ra
Net Charge 0
Average Mass 293.92400
Monoisotopic Mass 271.948
InChI InChI=1S/2ClH.Ra/h2*1H;/q;;+2/p-2/i;;1-3
InChIKey RWRDJVNMSZYMDV-SIUYXFDKSA-L
SMILES Cl[223Ra]Cl
Roles Classification
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
radiopharmaceutical
Any pharmaceutical compound containing a radioisotope.
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ChEBI Ontology
Outgoing 223RaCl2 (CHEBI:74895) has role antineoplastic agent (CHEBI:35610)
223RaCl2 (CHEBI:74895) has role radiopharmaceutical (CHEBI:35232)
223RaCl2 (CHEBI:74895) is a inorganic chloride (CHEBI:36093)
223RaCl2 (CHEBI:74895) is a isotopically modified compound (CHEBI:139358)
223RaCl2 (CHEBI:74895) is a radium molecular entity (CHEBI:37201)
IUPAC Name
(223Ra)radium dichloride
Synonym Source
Radium-223 dichloride KEGG DRUG
Brand Name Source
Xofigo KEGG DRUG
Manual Xrefs Databases
D10398 KEGG DRUG
Radium-223_chloride Wikipedia
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Registry Numbers Types Sources
444811-40-9 CAS Registry Number KEGG DRUG
444811-40-9 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
23682134 PubMed citation Europe PMC
23847352 PubMed citation Europe PMC
23863050 PubMed citation Europe PMC
Last Modified
30 January 2018