CHEBI:74729 - acriflavinium monochloride

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ChEBI Name acriflavinium monochloride
ChEBI ID CHEBI:74729
Definition A mixture comprising 3,6-diamino-10-methylacridinium chloride (usually 60-70%) and 3,6-diaminoacridine monohydrochloride (usually 40-30%).
Stars This entity has been manually annotated by the ChEBI Team.
Roles Classification
Biological Role(s): antibacterial agent
A substance that kills or slows the growth of bacteria.
carcinogenic agent
A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
intercalator
A role played by a chemical agent which exhibits the capability of occupying space between DNA base pairs due to particular properties in size, shape and charge. Intercalation of chemical compounds in DNA helix can result in replication errors (shift, mutation) or DNA damages.
Application(s): antiseptic drug
A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body).
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ChEBI Ontology
Outgoing acriflavinium monochloride (CHEBI:74729) has part 3,6-diamino-10-methylacridinium chloride (CHEBI:383703)
acriflavinium monochloride (CHEBI:74729) has part 3,6-diaminoacridine monohydrochloride (CHEBI:74718)
acriflavinium monochloride (CHEBI:74729) has role antibacterial agent (CHEBI:33282)
acriflavinium monochloride (CHEBI:74729) has role antiseptic drug (CHEBI:48218)
acriflavinium monochloride (CHEBI:74729) has role carcinogenic agent (CHEBI:50903)
acriflavinium monochloride (CHEBI:74729) has role intercalator (CHEBI:24853)
acriflavinium monochloride (CHEBI:74729) is a mixture (CHEBI:60004)
Synonym Source
acriflavinium chloride
Note: (2013-07-16) Note that the nomenclature is confusing: the British Pharmacopoeia uses the name acriflavinium chloride for this mixture of 3,6-diaminoacridine monohydrochloride and 3,6-diamino-10-methylacridinium chloride, although the same name, acriflavinium chloride, is the recommended International Nonproprietary Name for a mixture of 3,6-diaminoacridine dihydrochloride and 3,6-diamino-10-methylacridinium chloride hydrochloride.
ChEBI
Last Modified
16 July 2013