CHEBI:73275 - ospemifene

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ChEBI Name ospemifene
ChEBI ID CHEBI:73275
Definition An organochlorine compound that is a selective estrogen receptor modulator; used for treatment of dyspareunia.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C24H23ClO2
Net Charge 0
Average Mass 378.89100
Monoisotopic Mass 378.139
InChI InChI=1S/C24H23ClO2/c25-16-15-23(19-7-3-1-4-8-19)24(20-9-5-2-6-10-20)21-11-13-22(14-12-21)27-18-17-26/h1-14,26H,15-18H2/b24-23-
InChIKey LUMKNAVTFCDUIE-VHXPQNKSSA-N
SMILES OCCOc1ccc(cc1)C(\c1ccccc1)=C(\CCCl)c1ccccc1
Roles Classification
Application(s): estrogen receptor modulator
A substance that possess antiestrogenic actions but can also produce estrogenic effects as well. It acts as complete or partial agonist or as antagonist. It can be either steroidal or nonsteroidal in structure.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
anti-inflammatory agent
Any compound that has anti-inflammatory effects.
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ChEBI Ontology
Outgoing ospemifene (CHEBI:73275) has parent hydride stilbene (CHEBI:26775)
ospemifene (CHEBI:73275) has role anti-inflammatory agent (CHEBI:67079)
ospemifene (CHEBI:73275) has role antineoplastic agent (CHEBI:35610)
ospemifene (CHEBI:73275) has role estrogen receptor modulator (CHEBI:50739)
ospemifene (CHEBI:73275) is a aromatic ether (CHEBI:35618)
ospemifene (CHEBI:73275) is a organochlorine compound (CHEBI:36683)
ospemifene (CHEBI:73275) is a primary alcohol (CHEBI:15734)
IUPAC Name
2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}ethanol
Synonyms Sources
2-(4-(4-Chloro-1,2-diphenyl-but-1-enyl)phenoxy)ethanol ChemIDplus
2-(p-((Z)-4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)ethanol ChemIDplus
Deamino-hydroxytoremifene ChemIDplus
Fc-1271 ChemIDplus
FC-1271a ChemIDplus
ospemifene KEGG DRUG
Brand Name Source
Osphena KEGG DRUG
Database Links Databases
4749 DrugCentral
CN101636372 Patent
D08958 KEGG DRUG
EP2275098 Patent
EP2286806 Patent
Ospemifene Wikipedia
US2005182143 Patent
US2005187301 Patent
US2005187302 Patent
US2008207956 Patent
US2011015448 Patent
WO2005105052 Patent
WO2010107475 Patent
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Registry Numbers Types Sources
10283864 Reaxys Registry Number Reaxys
128607-22-7 CAS Registry Number KEGG DRUG
128607-22-7 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
22 February 2017