CHEBI:73041 - tilmacoxib

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ChEBI Name tilmacoxib
Definition A member of the class of 1,3-oxazoles that is that is 1,3-oxazole which is substituted at positions 2, 4 and 5 by methyl, cyclohexyl, and 3-fluoro-4-sulfamoylphenyl groups, respectively.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C16H19FN2O3S
Net Charge 0
Average Mass 338.39700
Monoisotopic Mass 338.11004
InChI InChI=1S/C16H19FN2O3S/c1-10-19-15(11-5-3-2-4-6-11)16(22-10)12-7-8-14(13(17)9-12)23(18,20)21/h7-9,11H,2-6H2,1H3,(H2,18,20,21)
SMILES Cc1nc(C2CCCCC2)c(o1)-c1ccc(c(F)c1)S(N)(=O)=O
Roles Classification
Biological Role(s): cyclooxygenase 2 inhibitor
A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2.
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ChEBI Ontology
Outgoing tilmacoxib (CHEBI:73041) has role cyclooxygenase 2 inhibitor (CHEBI:50629)
tilmacoxib (CHEBI:73041) is a 1,3-oxazoles (CHEBI:46812)
tilmacoxib (CHEBI:73041) is a organofluorine compound (CHEBI:37143)
tilmacoxib (CHEBI:73041) is a sulfonamide (CHEBI:35358)
INNs Sources
tilmacoxib WHO MedNet
tilmacoxib WHO MedNet
tilmacoxib WHO MedNet
tilmacoxibum WHO MedNet
Synonyms Sources
4-(4-cyclohexyl-2-methyloxazol-5-yl)-2-fluorobenzenesulfonamide ChemIDplus
5-ethoxymethyl-7-fluoro-3-oxo-1,2,3,5-tetrahydrobenzo(4,5)imidazo(1,2a)pyridine-4-N-(2-fluorophenyl)carboxamide ChemIDplus
JTE-522 ChemIDplus
JTP-19605 ChemIDplus
RWJ-57504 ChemIDplus
Manual Xrefs Databases
Tilmacoxib Wikipedia
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Registry Numbers Types Sources
180200-68-4 CAS Registry Number KEGG DRUG
180200-68-4 CAS Registry Number ChemIDplus
9005354 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
10807499 PubMed citation Europe PMC
11092987 PubMed citation Europe PMC
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16622748 PubMed citation Europe PMC
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Last Modified
27 March 2013