CHEBI:71311 - pyrazine-2-carboxylic acid

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ChEBI Name pyrazine-2-carboxylic acid
ChEBI ID CHEBI:71311
Definition The parent compound of the class of pyrazinecarboxylic acids, that is pyrazine bearing a single carboxy substituent. The active metabolite of the antitubercular drug pyrazinamide.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C5H4N2O2
Net Charge 0
Average Mass 124.09750
Monoisotopic Mass 124.027
InChI InChI=1S/C5H4N2O2/c8-5(9)4-3-6-1-2-7-4/h1-3H,(H,8,9)
InChIKey NIPZZXUFJPQHNH-UHFFFAOYSA-N
SMILES OC(=O)c1cnccn1
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): drug metabolite

antitubercular agent
A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis.
Application(s): antitubercular agent
A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis.
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ChEBI Ontology
Outgoing pyrazine-2-carboxylic acid (CHEBI:71311) has role antitubercular agent (CHEBI:33231)
pyrazine-2-carboxylic acid (CHEBI:71311) has role drug metabolite (CHEBI:49103)
pyrazine-2-carboxylic acid (CHEBI:71311) is a pyrazinecarboxylic acid (CHEBI:48345)
pyrazine-2-carboxylic acid (CHEBI:71311) is conjugate acid of pyrazine-2-carboxylate (CHEBI:71266)
Incoming pyrazine-2-carboxylate (CHEBI:71266) is conjugate base of pyrazine-2-carboxylic acid (CHEBI:71311)
IUPAC Name
pyrazine-2-carboxylic acid
Synonyms Sources
2-Carboxypyrazine NIST Chemistry WebBook
2-Pyrazinecarboxylic acid KEGG COMPOUND
Paradiazinecarboxylic acid NIST Chemistry WebBook
pyrazinecarboxylic acid ChEBI
Pyrazinemonocarboxylic acid ChemIDplus
Pyrazinic acid ChemIDplus
Pyrazinoic acid KEGG COMPOUND
Manual Xrefs Databases
C19915 KEGG COMPOUND
PYRAZINOIC-ACID MetaCyc
Pyrazinoic_acid Wikipedia
VGL PDBeChem
View more database links
Registry Numbers Types Sources
112305 Reaxys Registry Number Reaxys
98-97-5 CAS Registry Number KEGG COMPOUND
98-97-5 CAS Registry Number ChemIDplus
98-97-5 CAS Registry Number NIST Chemistry WebBook
Citations Waiting for Citations Types Sources
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Last Modified
08 June 2017