CHEBI:70727 - topoisomerase inhibitor

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ChEBI Name topoisomerase inhibitor
ChEBI ID CHEBI:70727
Definition An EC 5.99.1.* (miscellaneous isomerase) inhibitor that interferes with the action of any of the topoisomerases (enzymes that regulate the overwinding or underwinding of DNA).
Stars This entity has been manually annotated by the ChEBI Team.
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ChEBI Ontology
Outgoing topoisomerase inhibitor (CHEBI:70727) is a EC 5.99.1.* (miscellaneous isomerase) inhibitor (CHEBI:76830)
Incoming 2,2,3,3-tetrahydroxy-2,3-dihydronaphthalene-1,4-dione (CHEBI:78857) has role topoisomerase inhibitor (CHEBI:70727)
actinodaphnine (CHEBI:2444) has role topoisomerase inhibitor (CHEBI:70727)
EC 5.99.1.2 (DNA topoisomerase) inhibitor (CHEBI:50276) is a topoisomerase inhibitor (CHEBI:70727)
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor (CHEBI:50750) is a topoisomerase inhibitor (CHEBI:70727)
topoisomerase II inhibitor (CHEBI:156203) is a topoisomerase inhibitor (CHEBI:70727)
topoisomerase IV inhibitor (CHEBI:53559) is a topoisomerase inhibitor (CHEBI:70727)
Synonym Source
topoisomerase inhibitors ChEBI
Manual Xref Database
Topoisomerase Wikipedia
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Last Modified
16 July 2020