CHEBI:68293 - nagilactone F

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ChEBI Name nagilactone F
Definition A diterpene lactone isolated from Podocarpus latifolius and has been shown to exhibit inhibitory activity against activator protein 1 (AP-1).
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C19H24O4
Net Charge 0
Average Mass 316.39150
Monoisotopic Mass 316.16746
InChI InChI=1S/C19H24O4/c1-10(2)15-11-8-13-16-18(3,12(11)9-14(20)23-15)6-5-7-19(16,4)17(21)22-13/h8-10,13,15-16H,5-7H2,1-4H3/t13-,15-,16-,18-,19+/m1/s1
SMILES [H][C@@]12OC(=O)[C@@]3(C)CCC[C@](C)(C4=CC(=O)O[C@H](C(C)C)C4=C1)[C@@]23[H]
Metabolite of Species Details
Podocarpus latifolius (NCBI:txid120620) Found in root (BTO:0001188). Previous component: root bark; CH2Cl2-MeOH(1:1) extract of dried, ground root bark See: PubMed
Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
AP-1 antagonist
An antogonist that interferes with the action of activator protein 1 (AP-1).
View more via ChEBI Ontology
ChEBI Ontology
Outgoing nagilactone F (CHEBI:68293) has role AP-1 antagonist (CHEBI:67199)
nagilactone F (CHEBI:68293) has role metabolite (CHEBI:25212)
nagilactone F (CHEBI:68293) is a γ-lactone (CHEBI:37581)
nagilactone F (CHEBI:68293) is a δ-lactone (CHEBI:18946)
nagilactone F (CHEBI:68293) is a diterpene lactone (CHEBI:49193)
nagilactone F (CHEBI:68293) is a organic heterotetracyclic compound (CHEBI:38163)
Registry Numbers Types Sources
1399292 Reaxys Registry Number Reaxys
36912-00-2 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
19778011 PubMed citation Europe PMC
21306129 PubMed citation Europe PMC
Last Modified
21 August 2013