CHEBI:6801 - metformin

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ChEBI Name metformin
ChEBI ID CHEBI:6801
Definition A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C4H11N5
Net Charge 0
Average Mass 129.167
Monoisotopic Mass 129.10145
InChI InChI=1S/C4H11N5/c1-9(2)4(7)8-3(5)6/h1-2H3,(H5,5,6,7,8)
InChIKey XZWYZXLIPXDOLR-UHFFFAOYSA-N
SMILES CN(C)C(=N)NC(N)=N
Roles Classification
Chemical Role(s): environmental contaminant
Any minor or unwanted substance introduced into the environment that can have undesired effects.
Biological Role(s): xenobiotic
A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
Application(s): hypoglycemic agent
A drug which lowers the blood glucose level.
geroprotector
Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing metformin (CHEBI:6801) has functional parent biguanide (CHEBI:3095)
metformin (CHEBI:6801) has role environmental contaminant (CHEBI:78298)
metformin (CHEBI:6801) has role geroprotector (CHEBI:176497)
metformin (CHEBI:6801) has role hypoglycemic agent (CHEBI:35526)
metformin (CHEBI:6801) has role xenobiotic (CHEBI:35703)
metformin (CHEBI:6801) is a guanidines (CHEBI:24436)
metformin (CHEBI:6801) is conjugate base of metformin(1+) (CHEBI:90688)
Incoming metformin(1+) (CHEBI:90688) is conjugate acid of metformin (CHEBI:6801)
IUPAC Name
N,N-dimethyltriimidodicarbonic diamide
INNs Sources
metformin WHO MedNet
metformina WHO MedNet
metformine WHO MedNet
metforminum WHO MedNet
Synonyms Sources
1,1-dimethylbiguanide ChemIDplus
dimethylbiguanide ChemIDplus
dimethyldiguanide ChemIDplus
LA 6023 DrugBank
LA-6023 ChemIDplus
N,N-dimethylbiguanide ChemIDplus
N,N-dimethyldiguanide ChemIDplus
N,N-dimethylguanylguanidine DrugCentral
N,N-dimethylimidodicarbonimidic diamide IUPAC
N1,N1-dimethylbiguanide ChemIDplus
Manual Xrefs Databases
1725 DrugCentral
C07151 KEGG COMPOUND
D04966 KEGG DRUG
DB00331 DrugBank
FDB022739 FooDB
HMDB0001921 HMDB
LSM-4730 LINCS
Metformin Wikipedia
MF8 PDBeChem
View more database links
Registry Numbers Types Sources
606492 Reaxys Registry Number Reaxys
657-24-9 CAS Registry Number ChemIDplus
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Last Modified
10 June 2021
General Comment
2014-10-29 Stravs M, Schymanski E, Singer H, Department of Environmental Chemistry, Eawag