CHEBI:6722 - megestrol

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ChEBI Name megestrol
ChEBI ID CHEBI:6722
Definition A 3-oxo Δ4-steroid that is pregna-4,6-diene-3,20-dione substituted by a hydroxy group at position 17.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C22H30O3
Net Charge 0
Average Mass 328.44522
Monoisotopic Mass 328.20384
InChI InChI=1S/C21H28O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h4-5,12,16-18,24H,6-11H2,1-3H3/t16-,17+,18+,19+,20+,21+/m1/s1
InChIKey JBVNBBXAMBZTMQ-CEGNMAFCSA-N
SMILES [H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@]3(O)C(C)=O)[C@]1([H])C=CC1=CC(=O)CC[C@]21C
Roles Classification
Biological Role(s): progestin
A synthetic progestogen.
Application(s): contraceptive drug
A chemical substance that prevents or reduces the probability of conception.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
appetite enhancer
A drug which increases appetite.
synthetic oral contraceptive
An oral contraceptive which owes its effectiveness to synthetic preparation.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing megestrol (CHEBI:6722) has role antineoplastic agent (CHEBI:35610)
megestrol (CHEBI:6722) has role appetite enhancer (CHEBI:50779)
megestrol (CHEBI:6722) has role contraceptive drug (CHEBI:49323)
megestrol (CHEBI:6722) has role progestin (CHEBI:59826)
megestrol (CHEBI:6722) has role synthetic oral contraceptive (CHEBI:49326)
megestrol (CHEBI:6722) is a 17α-hydroxy steroid (CHEBI:35342)
megestrol (CHEBI:6722) is a 20-oxo steroid (CHEBI:36885)
megestrol (CHEBI:6722) is a 3-oxo-Δ4 steroid (CHEBI:47909)
megestrol (CHEBI:6722) is a tertiary α-hydroxy ketone (CHEBI:139592)
Incoming megestrol acetate (CHEBI:6723) has functional parent megestrol (CHEBI:6722)
IUPAC Name
17-hydroxypregna-4,6-diene-3,20-dione
INNs Sources
mégestrol ChEBI
megestrol ChEBI
megestrolum ChEBI
Synonyms Sources
17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione ChemIDplus
Megestrol KEGG COMPOUND
Brand Names Sources
Magestin Deprecated term DrugBank
Megeron Deprecated term DrugBank
Niagestin Deprecated term DrugBank
Ovaban Deprecated term DrugBank
Ovarid Deprecated term DrugBank
Volidan Deprecated term DrugBank
Manual Xrefs Databases
C07120 KEGG COMPOUND
D08167 KEGG DRUG
DB00351 DrugBank
Megestrol Wikipedia
View more database links
Registry Numbers Types Sources
3164843 Reaxys Registry Number Reaxys
3164843 Beilstein Registry Number Beilstein
3562-63-8 CAS Registry Number ChemIDplus
Citation Waiting for Citations Type Source
12161003 PubMed citation Europe PMC
Last Modified
07 February 2018