CHEBI:65411 - anolignan B

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ChEBI Name anolignan B
Definition A lignan that consists of buta-1,3-diene substituted by 4-hydroxybenzyl groups at positions 2 and 3. It is isolated from the ground stems of Anogeissus acuminata and exhibits anti-HIV activity by inhibiting HIV-1 reverse transcriptase enzyme.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C18H18O2
Net Charge 0
Average Mass 266.33430
Monoisotopic Mass 266.13068
InChI InChI=1S/C18H18O2/c1-13(11-15-3-7-17(19)8-4-15)14(2)12-16-5-9-18(20)10-6-16/h3-10,19-20H,1-2,11-12H2
SMILES Oc1ccc(CC(=C)C(=C)Cc2ccc(O)cc2)cc1
Metabolite of Species Details
Anogeissus acuminata (NCBI:txid155018) Found in stem (BTO:0001300). Ground stem See: PubMed
Roles Classification
Biological Role(s): HIV-1 reverse transcriptase inhibitor
An entity which inhibits the activity of HIV-1 reverse transcriptase.
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing anolignan B (CHEBI:65411) has role HIV-1 reverse transcriptase inhibitor (CHEBI:53756)
anolignan B (CHEBI:65411) has role metabolite (CHEBI:25212)
anolignan B (CHEBI:65411) is a lignan (CHEBI:25036)
anolignan B (CHEBI:65411) is a phenols (CHEBI:33853)
Synonyms Sources
2,3-bis-(4-hydroxybenzyl)-1,3-butadiene ChEBI
4,4'-(2,3-bis(methylene)-1,4-butanediyl)bisphenol ChemIDplus
Registry Numbers Types Sources
158081-98-2 CAS Registry Number ChemIDplus
7812590 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
16257162 PubMed citation Europe PMC
17828718 PubMed citation Europe PMC
7525878 PubMed citation Europe PMC
9249982 PubMed citation Europe PMC
Last Modified
07 November 2012