CHEBI:65410 - anolignan A

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ChEBI Name anolignan A
Definition A lignan that consists of buta-1,3-diene substituted by a 2,4-dihydroxybenzyl group at position 2 and a 1,3-benzodioxol-5-ylmethyl group at position 3. It is isolated from the ground stems of Anogeissus acuminata and exhibits anti-HIV activity by inhibiting HIV-1 reverse transcriptase enzyme.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C19H18O4
Net Charge 0
Average Mass 310.34380
Monoisotopic Mass 310.12051
InChI InChI=1S/C19H18O4/c1-12(7-14-3-6-18-19(9-14)23-11-22-18)13(2)8-15-4-5-16(20)10-17(15)21/h3-6,9-10,20-21H,1-2,7-8,11H2
SMILES Oc1ccc(CC(=C)C(=C)Cc2ccc3OCOc3c2)c(O)c1
Metabolite of Species Details
Anogeissus acuminata (NCBI:txid155018) Found in stem (BTO:0001300). Ground stem See: PubMed
Roles Classification
Biological Role(s): HIV-1 reverse transcriptase inhibitor
An entity which inhibits the activity of HIV-1 reverse transcriptase.
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing anolignan A (CHEBI:65410) has role HIV-1 reverse transcriptase inhibitor (CHEBI:53756)
anolignan A (CHEBI:65410) has role metabolite (CHEBI:25212)
anolignan A (CHEBI:65410) is a benzodioxoles (CHEBI:38298)
anolignan A (CHEBI:65410) is a lignan (CHEBI:25036)
anolignan A (CHEBI:65410) is a resorcinols (CHEBI:33572)
Synonym Source
2-(2',4'-dihydroxybenzyl)-3-(3'',4''-methylenedioxybenzyl)- 1,3-butadiene ChemIDplus
Registry Numbers Types Sources
158081-97-1 CAS Registry Number ChemIDplus
8578143 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
11777463 PubMed citation Europe PMC
7525878 PubMed citation Europe PMC
Last Modified
07 November 2012