CHEBI:64610 - tenocyclidine

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ChEBI Name tenocyclidine
Definition A tertiary amino compound that consists of cyclohexane having piperidin-1-yl and thiophen-2-yl groups attached at position 1. A dissociative anaesthetic drug with halluccinogenic and stimulant effects. Its effects are similar to those of phencyclidine (PCP, an analogue with the thienyl group replaced by phenyl), but it is rather more potent.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C15H23NS
Net Charge 0
Average Mass 249.41500
Monoisotopic Mass 249.15512
InChI InChI=1S/C15H23NS/c1-3-9-15(10-4-1,14-8-7-13-17-14)16-11-5-2-6-12-16/h7-8,13H,1-6,9-12H2
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): NMDA receptor antagonist
Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs.
Application(s): central nervous system stimulant
Any drug that enhances the activity of the central nervous system.
neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
Drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations and other alterations of mood and thinking.
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ChEBI Ontology
Outgoing tenocyclidine (CHEBI:64610) has role central nervous system stimulant (CHEBI:35337)
tenocyclidine (CHEBI:64610) has role hallucinogen (CHEBI:35499)
tenocyclidine (CHEBI:64610) has role neuroprotective agent (CHEBI:63726)
tenocyclidine (CHEBI:64610) has role NMDA receptor antagonist (CHEBI:60643)
tenocyclidine (CHEBI:64610) is a piperidines (CHEBI:26151)
tenocyclidine (CHEBI:64610) is a tertiary amino compound (CHEBI:50996)
tenocyclidine (CHEBI:64610) is a thiophenes (CHEBI:26961)
INNs Sources
tenociclidina ChemIDplus
tenocyclidine ChemIDplus
tenocyclidinum ChemIDplus
Synonyms Sources
1-[1-(thiophen-2-yl)cyclohexyl]piperidine ChEBI
thienyl cyclohexylpiperidine DrugBank
Manual Xrefs Databases
DB01520 DrugBank
Tenocyclidine Wikipedia
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Registry Numbers Types Sources
1246605 Beilstein Registry Number ChemIDplus
1246605 Reaxys Registry Number Reaxys
21500-98-1 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
11967623 PubMed citation Europe PMC
15230189 PubMed citation Europe PMC
16942853 PubMed citation Europe PMC
18324340 PubMed citation Europe PMC
20338869 PubMed citation Europe PMC
2538766 PubMed citation Europe PMC
9489512 PubMed citation Europe PMC
Last Modified
21 August 2012