CHEBI:63937 - cyclazosin

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name cyclazosin
Definition A monocarboxylic acid amide obtained by formal condensation of the carboxy group of furoic acid with the secondary amino group of 6,7-dimethoxy-2-[(4aR,8aS)-octahydroquinoxalin-1-yl]quinazolin-4-amine.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C23H27N5O4
Net Charge 0
Average Mass 437.49160
Monoisotopic Mass 437.20630
InChI InChI=1S/C23H27N5O4/c1-30-19-12-14-15(13-20(19)31-2)25-23(26-21(14)24)28-10-9-27(16-6-3-4-7-17(16)28)22(29)18-8-5-11-32-18/h5,8,11-13,16-17H,3-4,6-7,9-10H2,1-2H3,(H2,24,25,26)/t16-,17+/m0/s1
SMILES [H][C@]12CCCC[C@@]1([H])N(CCN2C(=O)c1ccco1)c1nc(N)c2cc(OC)c(OC)cc2n1
Roles Classification
Biological Role(s): adenosine A2A receptor antagonist
An antagonist at the A2A receptor.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing cyclazosin (CHEBI:63937) has role adenosine A2A receptor antagonist (CHEBI:53121)
cyclazosin (CHEBI:63937) is a aromatic amide (CHEBI:62733)
cyclazosin (CHEBI:63937) is a aromatic ether (CHEBI:35618)
cyclazosin (CHEBI:63937) is a furans (CHEBI:24129)
cyclazosin (CHEBI:63937) is a monocarboxylic acid amide (CHEBI:29347)
cyclazosin (CHEBI:63937) is a quinazolines (CHEBI:38530)
cyclazosin (CHEBI:63937) is a quinoxaline derivative (CHEBI:38771)
Incoming cyclazosin hydrochloride (CHEBI:63935) has part cyclazosin (CHEBI:63937)
Synonym Source
cis-1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)decahydroquinoxaline ChemIDplus
Registry Numbers Types Sources
139953-73-4 CAS Registry Number ChemIDplus
8020551 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
11036156 PubMed citation Europe PMC
11294762 PubMed citation Europe PMC
14634588 PubMed citation Europe PMC
15598431 PubMed citation Europe PMC
16213480 PubMed citation Europe PMC
17276073 PubMed citation Europe PMC
18037913 PubMed citation Europe PMC
18702011 PubMed citation Europe PMC
8666020 PubMed citation Europe PMC
8917649 PubMed citation Europe PMC
9851544 PubMed citation Europe PMC
9871765 PubMed citation Europe PMC
Last Modified
06 March 2014