CHEBI:63620 - rasagiline

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ChEBI Name rasagiline
ChEBI ID CHEBI:63620
Definition An indane that consists of 1-aminoindane bearing an N-propargyl substituent. A selective, irreversible monoamine oxidase-B inhibitor.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Anonymous
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Formula C12H13N
Net Charge 0
Average Mass 171.23830
Monoisotopic Mass 171.105
InChI InChI=1S/C12H13N/c1-2-9-13-12-8-7-10-5-3-4-6-11(10)12/h1,3-6,12-13H,7-9H2/t12-/m1/s1
InChIKey RUOKEQAAGRXIBM-GFCCVEGCSA-N
SMILES C#CCN[C@@H]1CCc2ccccc12
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): EC 1.4.3.4 (monoamine oxidase) inhibitor
An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of monoamine oxidase (EC 1.4.3.4).
Application(s): neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
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ChEBI Ontology
Outgoing rasagiline (CHEBI:63620) has role EC 1.4.3.4 (monoamine oxidase) inhibitor (CHEBI:38623)
rasagiline (CHEBI:63620) has role neuroprotective agent (CHEBI:63726)
rasagiline (CHEBI:63620) is a indanes (CHEBI:46940)
rasagiline (CHEBI:63620) is a secondary amine (CHEBI:32863)
rasagiline (CHEBI:63620) is a terminal acetylenic compound (CHEBI:73477)
IUPAC Name
(1R)-N-(prop-2-yn-1-yl)indan-1-amine
INN Source
rasagiline KEGG DRUG
Synonyms Sources
(1R)-N-propargylindan-1-amine ChEBI
(R)-indan-1-yl-prop-2-ynyl-amine ChEBI
(R)-N-2-Propynyl-1-indanamine ChemIDplus
RAS DrugBank
Manual Xrefs Databases
D08469 KEGG DRUG
DB01367 DrugBank
Rasagiline Wikipedia
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Registry Numbers Types Sources
136236-51-6 CAS Registry Number KEGG DRUG
136236-51-6 CAS Registry Number ChemIDplus
9194207 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
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Last Modified
02 May 2013