CHEBI:63220 - 8-oxo-dGTP

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name 8-oxo-dGTP
ChEBI ID CHEBI:63220
Definition A purine 2'-deoxyribonucleoside 5'-triphosphate having 8-oxo-7,8-dihydroguanine as the nucleobase.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C10H16N5O14P3
Net Charge 0
Average Mass 523.18040
Monoisotopic Mass 522.99066
InChI InChI=1S/C10H16N5O14P3/c11-9-13-7-6(8(17)14-9)12-10(18)15(7)5-1-3(16)4(27-5)2-26-31(22,23)29-32(24,25)28-30(19,20)21/h3-5,16H,1-2H2,(H,12,18)(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,17)/t3-,4+,5+/m0/s1
InChIKey BUZOGVVQWCXXDP-VPENINKCSA-N
SMILES Nc1nc2n([C@H]3C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O3)c(=O)[nH]c2c(=O)[nH]1
Roles Classification
Biological Role(s): mutagen
An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution.
mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
(via nucleoside triphosphate )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing 8-oxo-dGTP (CHEBI:63220) has role mutagen (CHEBI:25435)
8-oxo-dGTP (CHEBI:63220) is a purine 2'-deoxyribonucleoside 5'-triphosphate (CHEBI:37042)
8-oxo-dGTP (CHEBI:63220) is conjugate acid of 8-oxo-dGTP(3−) (CHEBI:63222)
Incoming 8-oxo-dGTP(3−) (CHEBI:63222) is conjugate base of 8-oxo-dGTP (CHEBI:63220)
IUPAC Name
2'-deoxy-8-oxo-7,8-dihydroguanosine 5'-(tetrahydrogen triphosphate)
Synonyms Sources
8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate ChemIDplus
8-oxo-7,8-dihydro-2'-dGTP MetaCyc
8-oxodeoxyguanosine triphosphate ChemIDplus
Manual Xref Database
CPD0-1905 MetaCyc
View more database links
Registry Numbers Types Sources
139307-94-1 CAS Registry Number ChemIDplus
8373155 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
15850400 PubMed citation Europe PMC
17804481 PubMed citation Europe PMC
Last Modified
21 November 2011