CHEBI:62935 - dehydroepiandrosterone 7-O-(carboxymethyl)oxime

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ChEBI Name dehydroepiandrosterone 7-O-(carboxymethyl)oxime
ChEBI ID CHEBI:62935
ChEBI ASCII Name dehydroepiandrosterone 7-O-(carboxymethyl)oxime
Definition The 7-oxime of dehydroepiandrosterone, substituted on the oxime oxygen by a carboxymethyl group.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C21H29NO5
Net Charge 0
Average Mass 375.45870
Monoisotopic Mass 375.20457
InChI InChI=1S/C21H29NO5/c1-20-7-5-13(23)9-12(20)10-16(22-27-11-18(25)26)19-14-3-4-17(24)21(14,2)8-6-15(19)20/h10,13-15,19,23H,3-9,11H2,1-2H3,(H,25,26)/t13-,14-,15-,19-,20-,21-/m0/s1
InChIKey ZVQQBKJJJZODIH-XDLUYZMFSA-N
SMILES [H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])C(C=C2C[C@@H](O)CC[C@]12C)=NOCC(O)=O
Roles Classification
Biological Role(s): immunological adjuvant
A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity.
Application(s): immunological adjuvant
A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing dehydroepiandrosterone 7-O-(carboxymethyl)oxime (CHEBI:62935) has functional parent dehydroepiandrosterone (CHEBI:28689)
dehydroepiandrosterone 7-O-(carboxymethyl)oxime (CHEBI:62935) has role immunological adjuvant (CHEBI:50847)
dehydroepiandrosterone 7-O-(carboxymethyl)oxime (CHEBI:62935) is a 3β-hydroxy-Δ5-steroid (CHEBI:1722)
dehydroepiandrosterone 7-O-(carboxymethyl)oxime (CHEBI:62935) is a ketoxime (CHEBI:24983)
IUPAC Name
({[(3β)-3-hydroxy-17-oxoandrost-5-en-7-ylidene]amino}oxy)acetic acid
Synonyms Sources
dehydroepiandrosterone-7-carboxymethyloxime ChEBI
DHEA 7-O-(carboxymethyl)oxime ChEBI
DHEA-7-CMO ChEBI
Registry Number Type Source
2402395 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
21541365 PubMed citation Europe PMC
9140773 PubMed citation Europe PMC
Last Modified
25 April 2017