CHEBI:60643 - NMDA receptor antagonist

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name NMDA receptor antagonist
ChEBI ID CHEBI:60643
Definition Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:60797
ChEBI Ontology
Outgoing NMDA receptor antagonist (CHEBI:60643) is a excitatory amino acid antagonist (CHEBI:60798)
Incoming (1R,2S)-nortilidine (CHEBI:77841) has role NMDA receptor antagonist (CHEBI:60643)
(R)-ketamine (CHEBI:580604) has role NMDA receptor antagonist (CHEBI:60643)
(R,R)-tramadol (CHEBI:75725) has role NMDA receptor antagonist (CHEBI:60643)
(R,R)-tramadol hydrochloride (CHEBI:75733) has role NMDA receptor antagonist (CHEBI:60643)
(S,S)-tramadol (CHEBI:75731) has role NMDA receptor antagonist (CHEBI:60643)
(S,S)-tramadol hydrochloride (CHEBI:75734) has role NMDA receptor antagonist (CHEBI:60643)
2-amino-5-phosphonopentanoic acid (CHEBI:138644) has role NMDA receptor antagonist (CHEBI:60643)
7-chlorokynurenic acid (CHEBI:63965) has role NMDA receptor antagonist (CHEBI:60643)
amantadine (CHEBI:2618) has role NMDA receptor antagonist (CHEBI:60643)
amantadine hydrochloride (CHEBI:2619) has role NMDA receptor antagonist (CHEBI:60643)
amantadine sulfate (CHEBI:78351) has role NMDA receptor antagonist (CHEBI:60643)
CGP 78608 (CHEBI:64061) has role NMDA receptor antagonist (CHEBI:60643)
CGP 78608 hydrochloride (CHEBI:64065) has role NMDA receptor antagonist (CHEBI:60643)
dextromethorphan (CHEBI:4470) has role NMDA receptor antagonist (CHEBI:60643)
dinitrogen oxide (CHEBI:17045) has role NMDA receptor antagonist (CHEBI:60643)
esketamine (CHEBI:60799) has role NMDA receptor antagonist (CHEBI:60643)
esketamine hydrochloride (CHEBI:60800) has role NMDA receptor antagonist (CHEBI:60643)
ethanol (CHEBI:16236) has role NMDA receptor antagonist (CHEBI:60643)
ginsenoside Rb3 (CHEBI:77153) has role NMDA receptor antagonist (CHEBI:60643)
isoliquiritigenin (CHEBI:310312) has role NMDA receptor antagonist (CHEBI:60643)
ketamine (CHEBI:6121) has role NMDA receptor antagonist (CHEBI:60643)
ketamine hydrochloride (CHEBI:650657) has role NMDA receptor antagonist (CHEBI:60643)
kynurenic acid (CHEBI:18344) has role NMDA receptor antagonist (CHEBI:60643)
memantine (CHEBI:64312) has role NMDA receptor antagonist (CHEBI:60643)
memantine hydrochloride (CHEBI:64323) has role NMDA receptor antagonist (CHEBI:60643)
noribogaine (CHEBI:146264) has role NMDA receptor antagonist (CHEBI:60643)
orphenadrine (CHEBI:7789) has role NMDA receptor antagonist (CHEBI:60643)
orphenadrine citrate (CHEBI:7790) has role NMDA receptor antagonist (CHEBI:60643)
orphenadrine hydrochloride (CHEBI:60902) has role NMDA receptor antagonist (CHEBI:60643)
pentamidine (CHEBI:45081) has role NMDA receptor antagonist (CHEBI:60643)
phencyclidine (CHEBI:8058) has role NMDA receptor antagonist (CHEBI:60643)
rolicyclidine (CHEBI:60805) has role NMDA receptor antagonist (CHEBI:60643)
tenocyclidine (CHEBI:64610) has role NMDA receptor antagonist (CHEBI:60643)
tramadol (CHEBI:9648) has role NMDA receptor antagonist (CHEBI:60643)
tramadol hydrochloride (CHEBI:32250) has role NMDA receptor antagonist (CHEBI:60643)
Synonyms Sources
N-methyl-D-aspartate receptor antagonist ChEBI
N-methyl-D-aspartate receptor antagonists ChEBI
N-methyl-D-aspartate receptor antagonists ChEBI
NMDA receptor antagonists ChEBI
NMDAR antagonist ChEBI
NMDAR antagonists ChEBI
Last Modified
06 March 2020